Results 151 to 160 of about 3,408,578 (301)

Starch-rich plant foods 780,000 y ago: Evidence from Acheulian percussive stone tools. [PDF]

open access: yesProc Natl Acad Sci U S A
Ahituv H   +9 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Beyond the Surface: Exploring Ancient Plant Food Processing through Confocal Microscopy and 3D Texture Analysis on Ground Stone Tools. [PDF]

open access: yesJ Archaeol Method Theory
Zupancich A   +5 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Capuchin monkeys can make and use stone tools. [PDF]

open access: yesLearn Behav, 2017
Wasserman EA, Thompson RKR.
europepmc   +1 more source

Chipped stone technological organization central place foraging and exchange on the Northern Great Plains

open access: yes, 2019
"Combines a vast array of data with evolutionary ecology to define patterns in how past peoples along the Missouri River used stone sources for crafting tools."--Provided by ...
Johnson, Craig M.
core  

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

open access: yesAdvanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy