Results 31 to 40 of about 715,228 (305)

Stone Tools in the High Molise Mountains (Italy): A first Report

open access: yesJournal of Lithic Studies, 2021
In the last decades, several researches focused on the inland areas of Molise Region (Central-Southern Italy) to investigate the occupation and exploitation of this environment during Pleistocene and Holocene.
Vittorio Mironti   +3 more
doaj   +1 more source

Archeometric Investigation of the Stone Tools of the Vatya Culture (Pest County, Hungary) [PDF]

open access: yes, 2014
With the analysis of the middle Bronze Age (2000–1350 BC) Vatya culture findings in Pest county (Central Hungary) comprising of more than 400 polished stone tools and instrument tools this is the first archaeometric study with such scale in Hungary.
Farkas-Pető, Anna   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Material Perspectives: Stone Tool Use and Material Culture in Papua New Guinea

open access: yesInternet Archaeology, 2003
Flaked stone tools are synonymous with prehistory to the extent that it is arguable that without these, the discipline would not exist. Yet we know relatively little about how people used them and what role they played within the material cultures of ...
Karen Hardy, Paul Sillitoe
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Data For: “Stone Tools in Upper Norrland: A Study of Stone Tools in Norrbottens County, Sweden”

open access: yesJournal of Open Archaeology Data
Much of the archived stone tool material found in Northern Sweden are stray finds not tied to an extensively documented archaeological site. This situation has led to artifacts seldom being revisited after being deposited in an archive. As a result, many
Love Eriksson, Michael A. Monzón
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Polished stone tools [PDF]

open access: yes, 2014
The first mention of polished stone tools from Bom Santo Cave is due to K. Lillios (2000), who has included this assemblage in a regional study alongside artefacts from other Neolithic and Chalcolithic sites in Estremadura.
Cardoso, João Luís
core  

Chimpanzee accumulative stone throwing [PDF]

open access: yes, 2016
The study of the archaeological remains of fossil hominins must rely on reconstructions to elucidate the behaviour that may have resulted in particular stone tools and their accumulation.
Abwe, Ekwoge   +80 more
core   +5 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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