Results 41 to 50 of about 3,408,578 (301)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The Early Neolithic Shoushma 10 Settlement at the Upper Course of the Konda River

Поволжская археология, 2020
Early Neolithic in the basin of the Konda River, the left tributary of the Irtysh River, is characterized by a large number of sites, a variety of their types and the original artifacts.
Klement'eva Tatiana Yu., Pogodin Andrey A., Dubovtсeva Ekaterina N.   +2 more
doaj   +1 more source

Do Chimpanzees Use Weight to Select Hammer Tools? [PDF]

, 2011
This study was financially supported by a Japan Society for the Promotion of Science Predoc Grant (http://www.jsps.go.jp/english/e-summer/index.html) to Cornelia Schrauf.
Josep Call, Schrauf, C., Schrauf, Cornelia (University of Vienna), Call, Josep, Schrauf Cornelia, Koki Fuwa, Hirata, Satoshi (Great Ape Research Institute, Hayashibara Biochemical Laboratories), Hirata, Satoshi, Satoshi Hirata, Fuwa, Koki, Hirata, S., Cornelia Schrauf, Hirata Satoshi, Fuwa, K., Call, J. ; https://orcid.org/, Fuwa Koki, Fuwa, Koki (Great Ape Research Institute, Hayashibara Biochemical Laboratories), Schrauf, Cornelia, Call Josep, Call, Josep (Department for Developmental and Comparative Psychology, Max Planck Institute for Evolutionary Anthropology)   +19 more
core   +2 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Eneolitization of the Forest Steppe Volga Region: cultural evolution or migration?

Археология евразийских степей
The source base for the Eneolithic of the forest steppe Volga region includes Eneolithic burial grounds and campsites. The data from the study of ceramics, stone, bone, metal tools, anthropological and archeozoological materials, radiocarbon dating were ...
Arkadii I. Korolev
doaj   +1 more source

Flaked Stone Tools of Holocene Sahul: Case studies from Northern Australia and Papua New Guinea

, 2021
This article reviews the Holocene records of flaked stone artefacts from the Sahul regions of New Guinea and northern Australia. Varied approaches to understanding the role of flaked stone tools in past societies have revealed novel insights into how ...
Maloney, Tim Ryan
core   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle, Cesar Alvarez‐Llamas, Vincent Motto‐Ros, Christophe Dujardin, Jérémie Margueritat, David Rodney   +5 more
wiley   +1 more source

Leveraging Symbolic Artificial Intelligence and Fuzzy Logic for Materials Science: A Review of Methods, Challenges, and Applications to Scarce and Imperfect Experimental Data

Advanced Engineering Materials, EarlyView.
This article explores the transformative potential of symbolic artificial intelligence (AI) in the field of materials science, particularly in leveraging experimental data. The article presents several symbolic AI models and discusses their applications in materials science.
Ahmed Amrani, Mohamed‐Ali Belloum, Laurence Boudet, Valentin Fouillard, Edwin Friedmann, Guillaume Lacharme, Ali Mahmoud, Jean‐Philippe Poli   +7 more
wiley   +1 more source

A Multi‐Scale Machine Learning Framework for the Inverse Design of High Entropy Alloys

Advanced Engineering Materials, EarlyView.
High‐entropy alloys offer vast potential for various applications, including electrocatalysis; however, their compositional complexity challenges conventional screening. We introduce an inverse‐design framework combining two neural networks to determine optimal compositions and reconstruct nanoparticle geometry from targeted properties and conventional
Mikael Takoutsin, Marta Campolucci, Nicolas de Andrade Ishiki, Nathan Mirgot, Nadir Zhamantay, Frédéric Kanoufi, Jennifer Peron, Jean Charlety, Emiliano Fonda, Valérie Briois, Marco Faustini, Maria‐Letizia De Marco, Christine Goyhenex, Ovidiu Ersen, Hervé Bulou   +14 more
wiley   +1 more source

Electrospun Wood‐Derived Biopolymers as Electrodes in Electrochemical Energy Storage Technologies

Advanced Functional Materials, EarlyView.
Electrospinning transforms wood‐derived cellulose and lignin into architecturally defined, binder‐free carbon electrodes with tuneable porosity and functionality. This review shows how fibre design enables decoupled charge and mass transport, enhancing performance across battery systems, while identifying key challenges in spinnability, scalability ...
Michael W. Thielke, Hattie R. Chisnall, Jesus Vazquez Chavez, Ana B. Jorge Sobrido   +3 more
wiley   +1 more source