Results 251 to 260 of about 270,897 (278)

Genetic code development by stop codon takeover

Journal of Theoretical Biology, 1988
A novel theoretical consideration of the origin and evolution of the genetic code is presented. Code development is viewed from the perspective of simultaneously evolving codons, anticodons and amino acids. Early code structure was determined primarily by thermodynamic stability considerations, requiring simplicity in primordial codes.
N, Lehman, T H, Jukes
openaire   +2 more sources

Regulated translational bypass of stop codons in yeast

Trends in Microbiology, 2007
Stop codons are used to signal the ribosome to terminate the decoding of an mRNA template. Recent studies on translation termination in the yeast Saccharomyces cerevisiae have not only enabled the identification of the key components of the termination machinery, but have also revealed several regulatory mechanisms that might enable the controlled ...
Tobias, von der Haar, Mick F, Tuite
openaire   +2 more sources

In vitro suppression of two different stop codons

Biotechnology and Bioengineering, 2016
ABSTRACTProteins play a crucial role in all living organisms, with the 20 natural amino acids as their building blocks. Unnatural amino acids are synthetic derivatives of these natural building blocks. These amino acids have unique chemical or physical properties as a result of their specific side chain residues.
Eden, Ozer, Yonatan, Chemla, Orr, Schlesinger, Haim Yuval, Aviram, Inbal, Riven, Gilad, Haran, Lital, Alfonta   +6 more
openaire   +2 more sources

Cancer syndromes and therapy by stop-codon readthrough

Trends in Molecular Medicine, 2012
Several hereditary cancer syndromes are associated with nonsense mutations that create premature termination codons (PTC). Therapeutic strategies involving readthrough induction partially restore expression of proteins with normal function from nonsense-mutated genes, and small molecules such as aminoglycosides and PTC124 have exhibited promising ...
Bordeira-Carriço, Renata, Pêgo, Ana Paula, Santos, Manuel, Oliveira, Carla   +3 more
openaire   +3 more sources

Stop Codon

2008
John B. Heppner, David B. Richman, Steven E. Naranjo, Dale Habeck, Christopher Asaro, Jean-Luc Boevé, Johann Baumgärtner, David C. Schneider, Paris Lambdin, Ronald D. Cave, Brett C. Ratcliffe, John B. Heppner, Rebecca W. Baldwin, Clay W. Scherer, J. Howard Frank, James C. Dunford, Louis A. Somma, David. B. Richman, E. S. Krafsur, Allen Crooker, John B. Heppner, John L. Capinera, Fabián D. Menalled, Matt Liebman, John L. Capinera, Peter E. A. Teal, Marjorie A. Hoy, James E. Lloyd, John Sivinski, Whitney Cranshaw, John B. Heppner, John B. Heppner, Peter H. Adler, John B. Heppner, James H. Tsai, Pauline O. Lawrence, Jennifer M. Zaspel, John B. Heppner, John L. Capinera, John B. Heppner, Oscar E. Liburd, Erin M. Sarzynski, Antônio R. Panizzi, Jamie Ellis, Amanda Ellis, Mark Headings, Antônio R. Panizzi, Paul D. Scotti, Peter D. Christian, Lionel Stange, John B. Heppner, John B. Heppner, Rebecca Baldwin, Robert K. Vander Meer, Catherine A. Preston, Gard W. Otis, Joseph W. Noling, Marjorie A. Hoy, Drion G. Bouicas, Allen Sanborn, Antônio R. Panizzi, David W. Ragsdale, John B. Heppner, Anthony Rossi, Marc Branham, Andrei Sourakov, Divina Amalin, Paula E. Cushing, Patrick De Clercq, Daniel C. Peck, Vinton Thompson, David E. Bowles, John L. Capinera, Vincent G. Nealis, John L. Capinera, James E. Cilek, Waldemar Klassen, Erich Tilgner, Miguel Costas, Ángeles Vázquez, Antônio R. Panizzi, Jorge R. Rey, Boris C. Kondratieff, Norbert H. Haunerland, Daniel A. Hahn, Jeffrey C. Lord, Jeyaraney Kathirithamby, Allan T. Showler, Rufolf H. Scheffrahn, Robert L. Meagher, Maria Gallo, Fiona F. Hunter, John B. Heppner, John B. Heppner, John B. Heppner, Dan Gerling, Pierre Jolivet, John L. Capinera, Seiichi Moriya, Marjorie A. Hoy, Roger F. Hou, Pauline O. Lawrence, Beverly Burden, Kun Yan Zhu, George Hangay   +104 more
openaire   +2 more sources

Deciphering the molecular mechanism of stop codon readthrough

Biological Reviews, 2021
Martine Palma, Fabrice Lejeune
exaly  

Stop Codon

2011
  +4 more sources

A polymorphic stop codon in BRCA2

Nature Genetics, 1996
S, Mazoyer, A M, Dunning, O, Serova, J, Dearden, N, Puget, C S, Healey, S A, Gayther, J, Mangion, M R, Stratton, H T, Lynch, D E, Goldgar, B A, Ponder, G M, Lenoir   +12 more
openaire   +2 more sources

Stop Codon

2006
openaire   +2 more sources

Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment

Nature, 2023
Kristína Záhonová, Jan Votypka, Eva Horáková   +2 more
exaly