Results 91 to 100 of about 470,402 (254)

A reaction-time adjusted PSI method for estimating performance in the stop-signal task.

open access: yesPLoS ONE, 2018
A central experimental task in executive control research is the Stop-signal task, which allows measuring the ability to inhibit dominant responses. A crucial aspect of this task consists of varying the delay between the Go- and Stop-signal.
Lorenz Weise   +4 more
doaj   +1 more source

The impact of yohimbine-induced arousal on facets of behavioural impulsivity [PDF]

open access: yes, 2012
Rationale State-dependent changes in physiological arousal may influence impulsive behaviours. Objectives To examine the relationship between arousal and impulsivity, we assessed the effects of yohimbine (an α2-adrenergic receptor antagonist, which ...
Herman, Aleksandra M   +2 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Evaluation of inhibitory control and attentional bias through eye-tracking: A modified emotional stop-signal task

open access: yesMethodsX
Obsessive-compulsive disorder (OCD) is characterized by deficits in inhibitory control and attentional processes. The emotional nature of stimuli can significantly influence these cognitive processes, yet traditional paradigms assessing inhibitory ...
Gonçalo Barros, Filipa Ribeiro
doaj   +1 more source

Stimulus-response mappings shape inhibition processes: a combined EEG-fMRI study of contextual stopping.

open access: yesPLoS ONE, 2014
Humans are rarely faced with one simple task, but are typically confronted with complex stimulus constellations and varying stimulus-relevance in a given situation.
Christina F Lavallee   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Inhibitory control in mind and brain 2.0: blocked-input models of saccadic countermanding. [PDF]

open access: yes, 2015
The interactive race model of saccadic countermanding assumes that response inhibition results from an interaction between a go unit, identified with gaze-shifting neurons, and a stop unit, identified with gaze-holding neurons, in which activation of the
Logan, Gordon D   +3 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Neural Mechanisms of Inhibitory Response in a Battlefield Scenario: a Simultaneous FMRI-EEG Study

open access: yesFrontiers in Human Neuroscience, 2016
The stop-signal paradigm has been widely adopted as a way to parametrically quantify the response inhibition process. To evaluate inhibitory function in realistic environmental settings, the current study compared stop-signal responses in two different ...
Li-Wei eKo   +4 more
doaj   +1 more source

Individual variability in the perceptual learning of L2 speech sounds and its cognitive correlates [PDF]

open access: yes, 2010
This study explored which cognitive processes are related to individual variability in the learning of novel phonemic contrasts in a second language.
Hazan, V., Kim, Y.H.
core  

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