Determining a Bayesian predictive power stopping rule for futility in a non-inferiority trial with binary outcomes [PDF]
Background/Aims: Non-inferiority trials investigate whether a novel intervention, which typically has other benefits (i.e., cheaper or safer), has similar clinical effectiveness to currently available treatments. In situations where interim evidence in a
Anna Heath +6 more
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Revisiting the stopping rule for hepatitis C genotype 1 patients treated with peginterferon plus ribavirin. [PDF]
BackgroundThe current stopping rule for peginterferon/ribavirin therapy in hepatitis C virus genotype-1 (HCV-1) patients is based on an early virological response (EVR, defined as >2 log(10) viral reduction at treatment week 12).
Ming-Lung Yu +11 more
doaj +2 more sources
Customizing Computerized Adaptive Test Stopping Rules for Clinical Settings Using the Negative Affect Subdomain of the NIH Toolbox Emotion Battery: Simulation Study [PDF]
BackgroundPatient-reported outcome measures are crucial for informed medical decisions and evaluating treatments. However, they can be burdensome for patients and sometimes lack the reliability clinicians need for clear clinical interpretations.
Saki Amagai +8 more
doaj +2 more sources
The goal is attainable: the effects of goal gradient and sub-goals on escalation of commitment in a new product evaluation [PDF]
Purpose – The purpose of this study is to investigate whether, in the context of making a go/no-go decision regarding a failing new product, the use of a stopping rule and/or a new decision-maker would reduce the escalation of commitment (EOC).
Beichen Liang
doaj +1 more source
Analyzing Stopping Behavior in Online Information Search Process from the Perspective of Information Foraging Theory [PDF]
This study analyzes search stopping points and stopping rules used in the online information search process based on the concepts of Information Foraging Theory. The research method is a descriptive-analytical study.
Fereshte Ilani +2 more
doaj +1 more source
Competitiveness motivates organizations to implement statistical approaches for improvement purposes. The literature offers a variety of quantitative methods intended to analyze and improve processes such as the design of experiments, steepest paths and ...
Paulo Eduardo García-Nava +3 more
doaj +1 more source
Familiarity with the landscape increases foraging efficiency and safety. Thus, when animals are confronted with a novel environment, either by natural dispersal or translocation, establishing a home range becomes a priority.
David Saltz +2 more
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Application of the professional maturity scale as a computerized adaptive testing
This study has two main purposes. Firstly, to compare the different item selection methods and stopping rules used in Computerized Adaptive Testing (CAT) applications with simulative data generated based on the item parameters of the Vocational Maturity ...
Süleyman Demir +2 more
doaj +1 more source
Towards monitored tomographic reconstruction: algorithm-dependence and convergence
The monitored tomographic reconstruction (MTR) with optimized photon flux technique is a pioneering method for X-ray computed tomography (XCT) that reduces the time for data acquisition and the radiation dose.
K.B. Bulatov +8 more
doaj +1 more source
When do stop-loss rules stop losses? [PDF]
Stop-loss rules - predetermined policies that reduce a portfolio's exposure after reaching a certain threshold of cumulative losses - are commonly used by retail and institutional investors to manage the risks of their investments, but have also been viewed with some skepticism by critics who question their efficacy.
Kaminski, Kathryn M., Lo, Andrew W
openaire +4 more sources

