Results 91 to 100 of about 49,874 (298)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

American options with multiple priors in continuous time [PDF]

We investigate American options in a multiple prior setting of continuous time and determine optimal exercise strategies form the perspective of an ambiguity averse buyer.
Jörg Vorbrink
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A robust complex local mean decomposition method with self‐adaptive sifting stopping

Electronics Letters
Targets with rotating components generate micro‐motion (MM) modulation effect in addition to the main body. Extracting MM parameters is challenging due to interference from the target's main body, necessitating the separation of modulation signals.
CanYu Mo, QianQiang Lin, YuanDuo Niu, HaoRan Du   +3 more
doaj   +1 more source

Preventing Posterior Collapse with DVAE for Text Modeling

Entropy
This paper introduces a novel variational autoencoder model termed DVAE to prevent posterior collapse in text modeling. DVAE employs a dual-path architecture within its decoder: path A and path B.
Tianbao Song, Zongyi Huang, Xin Liu, Jingbo Sun   +3 more
doaj   +1 more source

Infinite horizon stopping problems with (nearly) total reward criteria [PDF]

, 2014
We study an infinite horizon optimal stopping Markov problem which is either undiscounted (total reward) or with a general Markovian discount rate. Using ergodic properties of the underlying Markov process, we establish the feasibility of the stopping ...
Stettner, L, Palczewski, J
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Chain Reaction: A Youth-driven, Multimedia Storytelling Project Promoting Alternatives to Calling the Police

Journal of Curriculum Theorizing, 2013
The authors detail their work with Chain Reaction, a Chicago-based participatory action research and popular education project working to spark conversations about alternatives to calling the police on young people.
Sarah Brewster, Jane Hereth
doaj   +1 more source

Stopping set analysis of repeat multiple-accumulate codes

2009 IEEE International Symposium on Information Theory, 2009
In this work, we consider a stopping set analysis of repeat multiple-accumulate (RMA) code ensembles formed by the serial concatenation of a repetition code with multiple accumulators. The RMA codes are assumed to be iteratively decoded in a constituent code oriented fashion using maximum a posteriori erasure correction in the constituent codes.
Eirik Rosnes, Alexandre Graell i Amat
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source