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Safety and pharmacokinetics of GSK3494245, a highly selective Leishmaniasis kinetoplastid proteasome inhibitor for the treatment of visceral leishmaniasis: A Phase 1, randomized, single ascending dose escalation study in healthy participants. [PDF]
PLoS Negl Trop DisMoodley M +11 more
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It is time to stop meniscectomy
British Journal of Sports Medicine, 2017Recently, the New York Times asked why ‘useless’ surgery is still popular.1 In this editorial we outline three factors that likely promote continuing use of arthroscopic partial meniscectomy, for more than 350 000 middle-aged and older Americans (>35 years) annually.
Roos, Ewa M, Thorlund, Jonas Bloch
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The time course of psychophysical end-stopping
Vision Research, 1999 This study measured the time course of psychophysical end-stopping and compared it with the time course of masking. For a 10′ D6 target on an 18′ D6 pedestal, two abutting end-zone masks (each 13.5′ long) covering the filter end-zones reduce masking ...
Dennis M Levi
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Hexachlorophene — time to stop
Journal of Paediatrics and Child Health, 1980A review of the use of hexachlorophene in newborn nurseries is presented. The concern over safety is discussed. The lack of any controlled follow-up of babies treated with hexachlorophene is stressed. It is recommended that routine use of hexachlorophene be stopped and an infection monitoring committee consisting of an obstetrician paediatrician ...
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A ‘Non‐Stopping’ Time with the Optional‐Stopping Property
Bulletin of the London Mathematical Society, 2002An example is given of a random time ρ associated with Brownian motion such that ρ is not a stopping time but EMρ=EM0 for every uniformly integrable martingale M. 2000 Mathematics Subject Classification 60G40, 60G44.
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On Regression-Based Stopping Times
Discrete Event Dynamic Systems, 2009zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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2020
Withdrawal of life-sustaining medical technologies occurs frequently in children’s hospitals. It has been reported that more than 65% of pediatric patients die following withholding (nonescalation) or withdrawal of medical technology. As a result, pediatric providers must understand the nuances involved in the withdrawal of various forms of medical ...
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Withdrawal of life-sustaining medical technologies occurs frequently in children’s hospitals. It has been reported that more than 65% of pediatric patients die following withholding (nonescalation) or withdrawal of medical technology. As a result, pediatric providers must understand the nuances involved in the withdrawal of various forms of medical ...
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The Complexity of Tracking a Stopping Time
2007 IEEE International Symposium on Information Theory, 2007We present a generalization of the well-known Bayesian change-point detection problem. Specifically, let {(Xi,Yi)}iges1 be a sequence of pairs of random variables, and let S be a stopping time with respect to {Xi}iges1. We assume that the (Xi, Yi)'s take values in the same finite alphabet X times Y.
Urs Niesen +2 more
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