Results 81 to 90 of about 223,857 (311)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Absorption of energy exploitation during impact of aircraft
Aviation, 2004 The article shows the variation of stopping distance as a function of deceleration and velocity change derived from the standard Newtonian equations for assumed constant acceleration.
Antanas Žiliukas, Nina Fiodorova
doaj +1 more source
On an Effective Solution of the Optimal Stopping Problem for Random Walks [PDF]
We find a solution of the optimal stopping problem for the case when a reward function is an integer function of a random walk on an infinite time interval. It is shown that an optimal stopping time is a first crossing time through a level defined as the
Albert Shiryaev, Alexander Novikov
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
IEEE Photonics Journal, 2019 Optical stopping can serve as a light-controlled solution to implementing photonic components. In contrast to saturated optical stopping that provides enough excited electrons to entirely absorb signal lights, unsaturated optical stopping introduces a ...
Zhi Chen, Guande Wang, Xiong Wang
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Optimal multiple stopping time problem
, 2009 We study the optimal multiple stopping time problem defined for each stopping time $S$ by $\displaystyle{ v(S)=\esssup_ {\tau_1,\cdots,\tau_d \geq S } E[\psi( \tau_1,\cdots,\tau_d)\, |\,\F_S]\,}$.\\ The key point is the construction of a {\em new reward}
Kobylanski, Magdalena +2 more
core +3 more sources
Research of the stopping distance for different road conditions [PDF]
Transport Problems, 2011 In this paper a modern method for determination of stopping distance is represented. Application of the non-contact VBOX 3i 100Hz GPS Data Logger speed and distance measurement system is represented.
Daniel LYUBENOV
doaj
Optimal Stopping with Dynamic Variational Preferences [PDF]
We consider optimal stopping problems in uncertain environments for an agent assessing utility by virtue of dynamic variational preferences or, equivalently, assessing risk by dynamic convex risk measures.
Daniel Engelage
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source