Results 41 to 50 of about 3,753,682 (301)

Monitored Reconstruction: Computed Tomography as an Anytime Algorithm

open access: yesIEEE Access, 2020
Computed tomography is an important technique for non-destructive analysis of an object’s internal structure, relevant for scientific studies, medical applications, and industry.
Konstantin Bulatov   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Skorokhod Stopping Times Of Minimal Initial Expectation.

open access: yes, 1985
In this work, a class of stopping times for one-dimensional Brownian motion is examined--one which may be considered as the opposite of that studied by Root.
Gottron, Stephen Joseph
core   +5 more sources

Stopping games: recent results [PDF]

open access: yes
We survey recent results on the existence of the value in zero-sum stopping games with discrete and continuous time, and on the existence of e-equilibria in non zero-sum games with discrete time.stopping games; stochastic games ...
VIEILLE, Nicolas, SOLAN, Eilon
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Underground travel time estimation for macro simulation models, on the example of the first line in Warsaw

open access: yesBudownictwo i Architektura, 2014
In this paper, the author’s model of underground travel time prediction was presented. The structure of the model can be used to estimate the travel time of any underground line in the planning phase.
Marek Bauer
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Improving urban delivery with extended cargo bikes: a simulation-based study on the impact of double-parking on urban traffic flow

open access: yesEuropean Transport Research Review
This study investigates the impact of double-parking during pickup and delivery activities in urban areas for an innovative extended cargo bike concept consisting of a bicycle and up to five trailers.
Marcus Klatte, Tobias Kuhnimhof
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Microscale Modeling of Boarding and Alighting Processes at Shared-Use Bus Stops Under High Traffic Disruption

open access: yesApplied Sciences
With the growing heterogeneity of public transport systems, accurate representation of passenger service processes at bus stops shared by multiple operators has become increasingly important.
Justyna Stępień
doaj   +1 more source

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