Results 81 to 90 of about 2,163,301 (317)

Molecular Study of Dynamic Behavior between Head and Ultrathin Lubricant Film

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
The lubricant, perfluoropolyethers (PFPEs), has been modeled and analyzed using molecular dynamics simulations based on a coarse-grained bead-spring model.
Xiangjun LIU, Kensuke AMEMIYA, Chee How WONG, Shengkai YU, Bo LIU   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Modelling of high temperature storage systems for latent heat [PDF]

, 2009
There is a huge demand for heat storages for evaporation applications. Thermal storage systems are used to increase the efficiency of thermal systems by an improved adaption of energy availability and energy demand. In this paper a possible solution
Andreas Stückle, Stückle, Andreas
core   +1 more source

Orientation and Oviposition by Female Plodia interpunctella (Lepidoptera: Pyralidae) in Response to Volatiles from Varieties of Peanuts

Insects
Some special volatile organic compounds (VOCs) that significantly induce female oviposition preferences may be utilized to disrupt oviposition behavior and to enhance trapping strategies; such approaches offer a promising avenue for reducing insect ...
Xi Zhu, Dianxuan Wang, Fangfang Zeng, Liang Chen, Chen Wang, Sijia Shang, Zixin Guo   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Security challenges in cloud storage

, 2014
As cloud becomes the tool of choice for more data storage services, the number of service providers has also increased. With these choices, organisations have a wide selection of services available to move their data to the cloud.
Yahya, Fara, Chang, Victor, Wills, Gary B., Walters, Robert J.   +3 more
core  

Generalized Brewster effect in dielectric metasurfaces

Nature Communications, 2016
Devices with greater freedom are desired in nanophotonics. Here, the authors demonstrate theoretically and experimentally that the generalized Brewster effect can be observed in an all-dielectric metasurface potentially for any angle, wavelength and ...
Ramón Paniagua-Domínguez, Ye Feng Yu, Andrey E. Miroshnichenko, Leonid A. Krivitsky, Yuan Hsing Fu, Vytautas Valuckas, Leonard Gonzaga, Yeow Teck Toh, Anthony Yew Seng Kay, Boris Luk’yanchuk, Arseniy I. Kuznetsov   +10 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Storage games

The RAND Journal of Economics
ABSTRACT We study a long‐horizon, oligopolistic market with random shocks to demand that can be arbitraged by two storage operators with finite capacity. This problem applies to any storable commodity—that is, most commodities.
Sergei Balakin, Guillaume Roger
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source