Results 101 to 110 of about 5,285,726 (368)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Lithium-ion battery fault diagnosis method based on KPCA-MTCN

open access: yes工程科学学报
The paper proposes a method based on kernel principal component analysis (KPCA) and multi-scale temporal convolution network (MTCN) for identifying faults in lithium-ion batteries, which is crucial for ensuring the safe and stable operation of energy ...
Qipeng TAN   +5 more
doaj   +1 more source

Global and Local Sources of Risk in Eastern European Emerging Stock Markets [PDF]

open access: yes
We study a pricing model for global and local sources of risk in six Eastern European emerging stock markets. Utilizing GMM estimation and an unconditional asset-pricing framework with and without time-varying betas, we perform estimations based on ...
Elena Fedorova, Mika Vaihekoski
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Unifying the ORR and OER with surface oxygen and extracting their intrinsic activities on platinum

open access: yesNature Communications
Common half-cell measurements deliver oxygen reduction activities linked to the chosen scan rate, limiting their value for fundamental and comparative studies on platinum.
Benedikt Axel Brandes   +4 more
doaj   +1 more source

Determinants of Foreign Currency Borrowing in the New Member States of the EU [PDF]

open access: yes
The paper empirically investigates the determinants of foreign currency borrowing by the private sector in the new member states of the European Union. The authors find that striking differences in patterns of foreign currency borrowing between countries
Christoph Rosenberg, Marcel Tirpák
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Financial Crisis and the Stock Markets of the CEE Countries [PDF]

open access: yes
Stock markets in Central and Eastern European (CEE) countries significantly collapsed during the financial crisis of 2008. We studied whether the collapse of stock markets in CEE countries was due to international linkages of deteriorating fundamentals ...
Christian Pierdzioch, Renatas Kizys
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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