Results 91 to 100 of about 748,681 (316)

Low-Temperature Thermal-Energy Storage and Transmission Systems Employing Hydrophilic Polymeric Materials [PDF]

open access: yes, 1997
The wide fluctuations that occur in the aggregate electrical demand of a generating utility are punitive with respect to total system efficiency. Demand side management techniques have been applied to reduce such fluctuations including the conversion ...
Augood, P. C., Augood, P.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Optimization and operation of integrated homes with photovoltaic battery energy storage systems and power-to-heat coupling

open access: yesEnergy Conversion and Management: X, 2019
Renewable energies from residential photovoltaic systems can be used in the electricity sector as well as in the residential heating sector. Therefore, sector coupling, for example by using heat pump systems, is mandatory.
Georg Angenendt   +4 more
doaj   +1 more source

Optimization of information storage systems

open access: yesInformation and Control, 1968
In this paper the writers have developed a model and an optimization technique for the design of hierarchical structures of memory so as to minimize the average access time to blocks of information stored in the hierarchy for a given cost constraint. The assumption is made that the “activity profile” giving the relative frequencies with which blocks ...
K. Mani Chandy, Chittoor V. Ramamoorthy
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Design of alternative energy storage systems for hybrid vehicles based on statistical processing of driving cycles information [PDF]

open access: yes, 2011
Hybrid vehicles represent the future for automakers, since they allow to improve the fuel economy and to reduce the pollutant emissions. A key component of the hybrid powertrain is the Energy Storage System, that determines the ability of the vehicle to ...
Bolletta, Alberto
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Grid-scale battery energy storage systems [PDF]

open access: yes, 2013
textThis report presents an overview of the engineering considerations involved in the design of grid-scale battery energy storage systems. Grid-scale is defined here as systems over 1 MW in rated power, typically operated by a utility, independent power
Hill, Cody Aaron
core  

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