Results 101 to 110 of about 2,044,947 (320)
Are all reversible computations tidy?
, 2004 It has long been known that to minimise the heat emitted by a deterministic computer during it's operation it is necessary to make the computation act in a logically reversible manner\cite{Lan61}.
Maroney, O. J. E.
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Stochastic optimization model for random demand stocks, with storage expenses accounting
MATEC Web of Conferences, 2017 The paper presents a possible stock level optimization method, based on a stochastic model. The consume demand for the stored product is considered a discrete random quantity.
Ciolan Gheorghe +2 more
doaj +1 more source
BioTechniques, 1996 We describe a method using an inexpenive craft glue to routinely isolate specific areas of tissue as small as 1 mm2 from paraffin sections. The tissue may be digested to release nucleic acid suitable for PCR or reverse transcription PCR.
Gavin R. Turbett +3 more
doaj +1 more source
A Tabu Search Heuristic Procedure for the Capacitated Facility Location Problem [PDF]
A tabu search heuristic procedure for the capacitated facility location problem is developed, implemented and computationally tested. The heuristic procedure uses both short term and long term memories to perform the main search process as well as the ...
Minghe Sun
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Ontology-Based Search Procedure to Identify Tissue Samples in an Autopsy Archive: A Pilot Study
Applied Medical Informatics, 2018 This study aimed to obtain a detailed record of all autopsy specimens analyzed in the Pathology Department of the Emergency Clinical Hospital for Children, Cluj-Napoca from 1974 to 2018, by using an ontology-based search procedure (OSP) intended to ...
Bogdan POP +6 more
doaj
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e ZootecniaThe biotechnology used in tendon, bone and joint recoveries in Equine Medicine has improved in recent years. The most used are platelet rich plasma and stem cells from adipose tissue and bone marrow. However, recent studies have shown that stem cells can
J.O. Bernardo +4 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source