Results 101 to 110 of about 7,063,150 (343)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Stochastic optimization model for random demand stocks, with storage expenses accounting

open access: yesMATEC Web of Conferences, 2017
The paper presents a possible stock level optimization method, based on a stochastic model. The consume demand for the stored product is considered a discrete random quantity.
Ciolan Gheorghe   +2 more
doaj   +1 more source

Contribution to studying the structural analysis of rocket fuel

open access: yesVojnotehnički Glasnik, 1995
A brief review of possible stresses and deformation of rocket fuel while stored, in its preparation for exploitation and in the course of exploitation. The procedure of its structural analysis is described and shortcomings of the calculation based on the
Miloš Čolaković
doaj   +1 more source

Controlled crack growth specimen for brittle systems [PDF]

open access: yes
A pure Mode 1 fracture specimen and test procedure has been developed which provides extended, stable, through-thickness crack growth in ceramics and other brittle, nonmetallic materials.
Brewer, David N., Calomino, Anthony M.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Experimental Conditions to Obtain Photopolymerization Induced Phase Separation Process in Liquid Crystal-Photopolymer Composite Materials under Laser Exposure

open access: yesInternational Journal of Polymer Science, 2014
We analyze the experimental conditions necessary to obtain a photopolymerization induced phase separation process inside liquid crystal-photopolymer composite materials.
Manuel Ortuño   +4 more
doaj   +1 more source

Single-Tube Protocol for the Extraction of DNA or RNA from Paraffin-Embedded Tissues Using a Starch-Based Adhesive

open access: yesBioTechniques, 1996
We describe a method using an inexpenive craft glue to routinely isolate specific areas of tissue as small as 1 mm2 from paraffin sections. The tissue may be digested to release nucleic acid suitable for PCR or reverse transcription PCR.
Gavin R. Turbett   +3 more
doaj   +1 more source

Are all reversible computations tidy?

open access: yes, 2004
It has long been known that to minimise the heat emitted by a deterministic computer during it's operation it is necessary to make the computation act in a logically reversible manner\cite{Lan61}.
Maroney, O. J. E.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Ontology-Based Search Procedure to Identify Tissue Samples in an Autopsy Archive: A Pilot Study

open access: yesApplied Medical Informatics, 2018
This study aimed to obtain a detailed record of all autopsy specimens analyzed in the Pathology Department of the Emergency Clinical Hospital for Children, Cluj-Napoca from 1974 to 2018, by using an ontology-based search procedure (OSP) intended to ...
Bogdan POP   +6 more
doaj  

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