Results 111 to 120 of about 738,126 (291)

Atividade enzimática em plântulas de eucalyptus grandis provenientes de sementes envelhecidas artificialmente e naturalmente

open access: yesCiência Florestal, 2000
This research studied the standard procedure developed for crop seeds to examine the biochemical processes in accelerated aging seeds (kept for 96 hours at 42ºC and 100% RH) and stored seeds (from 5, 10 and 15 years) using isoenzyme electrophoresis and
Maria Letícia Camargo Pereira de   +4 more
doaj  

Pairing Analogy-Augmented Generation with Procedural Memory for Procedural Q&A [PDF]

open access: yesarXiv
Large language models struggle to synthesize disparate pieces of information into a coherent plan when approaching a complex procedural task. In this work, we introduce a novel formalism and structure for such procedural knowledge. Based on this formalism, we present a novel procedural knowledge dataset called LCStep, which we created from LangChain ...
arxiv  

Information Maps: A Practical Approach to Position Dependent Parameterization [PDF]

open access: yesarXiv, 2013
In this contribution a practical approach to determine and store position dependent parameters is presented. These parameters can be obtained, among others, using experimental results or expert knowledge and are stored in 'Information Maps'. Each Information Map can be interpreted as a kind of static grid map and the framework allows to link different ...
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee   +16 more
wiley   +1 more source

P61The possible impact of storing fetal samples collected during prenatal invasive procedures: case report [PDF]

open access: bronze, 2000
D. A. L. Pedreira   +4 more
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls   +9 more
wiley   +1 more source

First experience and clinical results of DSAEK utilizing the pre-cut ultrathin grafts

open access: yesОфтальмохирургия, 2013
Purpose. To evaluate the clinical functional efficiency of pre-cut donor corneas stored in the original preservation medium for the Ultrathin DSAEK procedure. Material and methods.
B.E. Malyugin,   +4 more
doaj  

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