Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
FIRST EXPERIENCE AND CLINICAL RESULTS OF DSAEK UTILIZING THE PRE-CUT ULTRATHIN GRAFTS
Офтальмохирургия, 2015 Purpose. To evaluate the clinical functional efficiency of precut donor corneas stored in the original preservation medium for the Ultrathin DSAEK procedure. Material and methods.
B. E. Malyugin +5 more
doaj
Recording and reproduction of microwave holograms using a scanning procedure and their subsequent optical processing [PDF]
Intensity distributions in nonoptical wave fields can be visualized and stored on photosensitive material. In the case of microwaves, temperature effects can be utilized with the aid of liquid crystals to visualize intensity distributions.
Hetsch, J.
core +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Calculation of Alr-Distribution while Storing Agricultural Products in Temporary Works
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2006 Using calculus techniques of solving filter equations the investigation has been carried out to find air distribution in cross-section area of storing bunkers and trenches. The engineering procedure has been suggested to estimate processes of air flow in
P. I. Dziachek
doaj
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
SPE 921(A) Current Perspective On Gas Well Testing Objectives, Methods, Procedures, Analysis And Requirements Of Producers, Purchasers, Storers And Regulators - Producers [PDF]
, 1964 Jack Schrenkel
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source