Results 71 to 80 of about 5,226,790 (259)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Monitoring of total contents of copper in organically and conventionally managed soils. Part 1: Study plan and …preliminary sampling of copper and other anthropogenic …induced heavy metal contents in vineyard soils

Journal für Kulturpflanzen, 2010
The project aims to develop a survey designed for the representative assessment of copper contents in vineyard soils. The method development for the sampling of adequate monitoring areas is based on a preliminary survey of load distribution as well as on
Frank Riepert, Anna Steindl, Rudolf Eibach, Michael Maixner, Christoph Reichmuth, Jörn Strassemeyer, Thomas Strumpf   +6 more
doaj   +1 more source

Study on the insecticidal activity compounds of the essential oil from Syzygium aromaticum against stored grain insect pests [PDF]

, 2010
Insect pests are a major cause of damage in stored grain around the world. To control the stored grain insects, synthetic insecticides have been used extensively for many years, resulting in insect populations that are resistant to insecticides ...
Liang, G. W., Lao, C. Z., Cen, Y. J., Zeng, L.   +3 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Essential oil nanoemulsions enhance protection of stored tobacco against Lasioderma serricorne

Scientific Reports
Essential oils present a promising botanical insecticide for sustainable pest control. Sourced from plants such as cinnamon, clove, and peppermint, these biocompounds are eco-friendly alternatives to conventional pesticides, employing unique modes of ...
Magdy A. Massoud, Abdelfattah S. A. Saad, Hassan A. Mesbah, Rasha A. Zinhoum, Marwa I. Mackled, Adel M. Khider, Khaled H. M. Abdel-Rheim   +6 more
doaj   +1 more source

Lethal effect of sulfuryl fluoride on eggs of different age of the Indian meal moth Plodia interpunctella (Hübner) – demonstration of the no constancy of the ct product for control

Journal für Kulturpflanzen, 2011
One to four day old eggs of the Indian meal moth Plodia interpunctella served for an investigation of their tolerance towards sulfuryl fluoride (SF) fumigation at 27°C and 65% relative humidity and of the question of constancy of the lethal dosage of SF –
Dalia A. Barakat, Gabriele Flingelli, Christoph Reichmuth   +2 more
doaj   +1 more source

Toxicity of four Cuban botanical derivatives against two stored-products coleopteran pests: Poster [PDF]

, 2018
Plants are a source of substances for protection of stored products. The Cuban flora has not yet been fully studied as a source of pesticides for postharvest protection, partly due to its great diversity.
Herrera, Rafael S., Pérez, Juan Carlos, González, Sayonara, Valenciaga, Nurys, Pérez, Oriela Pino, Fortes, Dayleni, Ramirez, Susana, Suris, Moraima, Sánchez, Yaima, Pino Pérez, Oriela   +9 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Toxicity of some Plant Oils under Different Temperatures against Stored Grain Insects, Sitophilus oryzae and Rhyzopertha dominica [PDF]

Journal of Plant Protection and Pathology
Sitophilus oryzae and Rhyzopertha dominica are serious insect pests of stored products in Egypt. The use of plant materials rather than conventional insecticides to control these insects is a promising alternative to neurotoxic insecticides.
ahmed Omar, George Nasr, T. Ismail, M. El-Ebiary   +3 more
doaj   +1 more source

Fumigant toxicity of essential oils and their combinations on population buildup of three stored product coleoptera in stored wheat and effect on quality of wheat: Poster [PDF]

, 2018
Experiments carried out to find the fumigant toxicity of three essential oils and their combinations from Murraya koenigii, Citrus reticulata, Curcuma longa on population buildup of Sitophilus oryzae, Rhyzopertha dominica, Tribolium castaneum in stored ...
Pandey, P. S., Kumar, Ranjeet, Tiwari, S. N.   +2 more
core   +1 more source