Results 51 to 60 of about 1,401,612 (387)

easySTORM: a robust, lower-cost approach to localisation and TIRF microscopy [PDF]

open access: yes, 2016
TIRF and STORM microscopy are super-resolving fluorescence imaging modalities for which current implementations on standard microscopes can present significant complexity and cost. We present a straightforward and low-cost approach to implement STORM and
Davies, T   +8 more
core   +1 more source

Storm and fire disturbances in Europe: Distribution and trends

open access: yesGlobal Change Biology, 2021
Abiotic forest disturbances are an important driver of ecosystem dynamics. In Europe, storms and fires have been identified as the most important abiotic disturbances in the recent past.
Cornelius Senf, R. Seidl
semanticscholar   +1 more source

Extreme Value Analysis of Ground Magnetometer Observations at Valentia Observatory, Ireland

open access: yesSpace Weather, 2023
Understanding global space weather effects is of great importance to the international scientific community, but more localized space weather predictions are important on a national level.
Alexandra Ruth Fogg   +7 more
doaj   +1 more source

COVID‐19 in Nursing Homes: Calming the Perfect Storm

open access: yesJournal of The American Geriatrics Society, 2020
The pandemic of viral infection with the severe acute respiratory syndrome coronavirus‐2 that causes COVID‐19 disease has put the nursing home industry in crisis.
J. Ouslander, D. Grabowski
semanticscholar   +1 more source

Cytokine Storm: The Primary Determinant for the Pathophysiological Evolution of COVID-19 Deterioration

open access: yesFrontiers in Immunology, 2021
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global health and has posed significant challenges for the treatment of severely ill COVID-19 ...
Ruirong Chen   +8 more
semanticscholar   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Deep-STORM: super-resolution single-molecule microscopy by deep learning [PDF]

open access: yes, 2018
We present an ultra-fast, precise, parameter-free method, which we term Deep-STORM, for obtaining super-resolution images from stochastically-blinking emitters, such as fluorescent molecules used for localization microscopy.
Elias Nehme   +7 more
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Book Review: Disasters and their relation with forests - Three case studies to support extreme events management

open access: yesForest@, 2021
This book review is a reworked and translated version of the synthesis from the report “Forest-related disasters - Three case studies and lessons for management of extreme events” by H. van Hensbergen and J.
Chiavetta U
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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