Results 51 to 60 of about 474,342 (308)

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

Inflammation Research, 2020
Novel Coronavirus disease 2019 (COVID-19), is an acute respiratory distress syndrome (ARDS), which is emerged in Wuhan, and recently become worldwide pandemic.
G. Meftahi, Z. Jangravi, H. Sahraei, Z. Bahari   +3 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Iris melanoma presenting as childhood glaucoma

American Journal of Ophthalmology Case Reports, 2018
Purpose: To describe the natural history and management of a rare case of iris melanoma in a pediatric patient. Observations: A Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly ...
Briana C. Gapsis, Nichelle A. Warren, Matthew J. Nutaitis, Leah A. Bonaparte, Samuel L. Cooper, Michael Ashenafi, Hans E. Grossniklaus, George N. Magrath   +7 more
doaj   +1 more source

The Influence of Reef Topography on Storm-Driven Sand Flux

Journal of Marine Science and Engineering, 2021
Natural formations of rock and coral can support geologically controlled beaches, where the beach dynamics are significantly influenced by these structures.
Cyprien Bosserelle, Shari L. Gallop, Ivan D. Haigh, Charitha B. Pattiaratchi   +3 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Storm and fire disturbances in Europe: Distribution and trends

Global Change Biology, 2021
Abiotic forest disturbances are an important driver of ecosystem dynamics. In Europe, storms and fires have been identified as the most important abiotic disturbances in the recent past.
Cornelius Senf, R. Seidl
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Foreseeing the reliability indexes of two-cascade thermo-electric cooling device in the mode of ΔTmax

Технологія та конструювання в електронній апаратурі, 2009
There has been offered a correlation model of reliability indexes for two-cascade TED of set design with basic meaningful parameters at successive electric connection of cascades.
V. P. Zaykov, L. A. Kinshova, V. F. Moiseev, L. D. Kazanghi, D. A. Klyuchnikov   +4 more
doaj  

No evidence for active viral infection in unicentric and idiopathic multicentric Castleman disease by Viral-Track analysis

Scientific Reports
Castleman disease (CD) is a rare hematologic disorder characterized by pathologic lymph node changes and a range of symptoms due to excessive cytokine production.
Ira Miller, Melanie D. Mumau, Saishravan Shyamsundar, Mateo Sarmiento Bustamante, Pedro Horna, Michael V. Gonzalez, David C. Fajgenbaum   +6 more
doaj   +1 more source