Results 171 to 180 of about 9,312 (215)

Weichselian history of the Fennoscandian Ice Sheet centre, Kvarken archipelago, western Finland—flow shifts, thermal regime and deglaciation

open access: yesBoreas, EarlyView.
Rapid thaw of the Earth's cryosphere in response to anthropogenic warming highlights the need to identify and understand the contrasting signatures of past ice‐sheet stability and collapse. The Kvarken archipelago, western Finland, at the centre of the former Fennoscandian Ice Sheet (FIS), has been designated a UNESCO World Heritage site in recognition
Niko Putkinen   +6 more
wiley   +1 more source

Reconstruction of Extreme Sea Levels in coastal China using Multiple Deep Learning models. [PDF]

open access: yesSci Data
Fang J   +8 more
europepmc   +1 more source

Submerged geomorphic record of Quaternary palaeoshorelines: terraces and clinothems along a shelf‐edge in the Žirje Archipelago, Adriatic Sea

open access: yesBoreas, EarlyView.
Numerous studies have shown that during the Quaternary there were substantial fluctuations in sea level in response to glacial–interglacial climate variability, reaching lowstand positions up to 134 m below the present sea level (b.s.l.). These fluctuations have had a strong influence on the morphology of shallow shelf seas, which preserve evidence of ...
Ozren Hasan   +7 more
wiley   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

open access: yesBritish Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

open access: yesCancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo   +6 more
wiley   +1 more source

Scalable Computation of Topological Abstractions for Scalar Data

open access: yesComputer Graphics Forum, EarlyView.
Abstract Topological data analysis has become an important tool for large scale scalar data analysis and visualization, efficiently extracting the inherent structure and features of interest of the data. However, with growing dataset sizes and complexity, it is increasingly becoming infeasible to compute topological abstractions of interest in serial ...
M. Will   +6 more
wiley   +1 more source

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