Results 1 to 4 of about 9 (4)
A novel and safe SmartCap<sup>®</sup> SC101 to develop the COVID-19 mRNA vaccine STP2104 inducing potent immune responses in humans. [PDF]
Front ImmunolWe have developed a 5′-capping library screening (CLS) method using over 30 different novel cap analogues. The optimal 5′-cap for the coronavirus disease 2019 (COVID-19) mRNA vaccine STP2104 was selected and applied. This is the first report to describe the proven safety of the novel cap analogue, SmartCap® SC101, in humans and emphasize the importance Kim R, Uhm TG, Kim J, Woo D, Kim UI, Meng X, Yang B, Kim S, Kim H, Kim J, Yoon S, Lee JY, Kim B, Cho D, Chang D, Cho YH, Choi K, Gwak W, Lee HW, Bang J, Hellström E, Kim B, Kim K, Yang JS. +23 moreeuropepmc +7 more sourcesDiscovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method. [PDF]
Front ImmunolMessenger RNA (mRNA) vaccines represent a critical avenue for coronavirus disease 2019 (COVID-19) prevention. We developed a COVID-19 mRNA vaccine encoding a codon-optimized full-length ancestral spike (S) protein with a signal peptide, which employs our novel patented co-transcriptional 5′-capping reagent, SmartCap®. From the screening capping library Choi K, Lee JY, Kim UI, Park SH, Hong SH, Bang YJ, Hwang YH, Lee JE, Park S, Kim S, Lee S, Yun YJ, Uhm TG, Lee I, Kwon M, Kwon E, Song S, Kweon Y, Kim H, Oh EY, Kim JY, Lee TY, Kim SY, Kim SE, Kim YJ, Lee S, Sun R, Lee EJ, Kim G, Lim H, Kim B, Kim J, Kim D, Nam JH, Lee SM, Kim K, Yang JS. +36 moreeuropepmc +5 more sourcesTable 1_Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method.docx
Kanghyun Choi (21507536), Joo-Young Lee (3351287), Uk-Il Kim (11172120), So-Hyun Park (1604836), So-Hee Hong (11476165), Yoo-Jin Bang (13912929), Yun-Ho Hwang (7140257), Jong-Eun Lee (225501), Suhyun Park (4517539), Soochong Kim (9397470), Sunhee Lee (357876), Ye-Jin Yun (21507539), Tae-Gi Uhm (21507542), Inyoung Lee (4053886), Minju Kwon (17651880), EunJi Kwon (21507545), Suyeon Song (21507548), Yongkyoung Kweon (21507551), Heejene Kim (21507554), Eun-Young Oh (15082237), Jae-Yong Kim (3220101), Tae-Young Lee (3083049), Seo-Yeon Kim (10300453), Se-Eun Kim (8482638), You-Jin Kim (427871), Seonock Lee (12319943), Ruijing Sun (12319946), Eun-Joo Lee (6494516), Gamin Kim (714450), Hanah Lim (21507578), Byungkyun Kim (21507599), Jungho Kim (577190), Dokeun Kim (17599154), Jae-Hwan Nam (670465), Sang-Myeong Lee (806173), Kyungjin Kim (140317), Joo-Sung Yang (4479568) +36 moreopenalex +1 more source
