Results 141 to 150 of about 96,669 (282)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Relationship between the Number of Carbon Chains and the Antifungal Activity of 9-Straight Chain Alkylated Acridine Derivatives

, 1999
G. FUKATA, Akira Kitamura, kuniharu TAKAHASHI, Akiyoshi Torii, Kichinosuke Kamata, Tadashi Yonemitsu, Masashi Tashiro, Shuntarō Mataka   +7 more
openalex   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Intestinal permeability enhancement of levothyroxine sodium by straight chain fatty acids studied in MDCK epithelial cell line

, 2010
Dimple Pabla, Fatemeh Akhlaghi, Hossein Zia   +2 more
openalex   +2 more sources

cDNA cloning and analysis of tissue‐specific expression of mouse peroxisomal straight‐chain acyl‐CoA oxidase [PDF]

, 2000
Christa Nöhammer, Yosuf El‐Shabrawi, Silvia Schauer, M. Hiden, Johannes Berger, Sonja Forss‐Petter, Elke Winter, Robert Eferl, Rudolf Zechner, Gerald Höefler   +9 more
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry. [PDF]

J Chromatogr B Analyt Technol Biomed Life Sci, 2018
He L, Prodhan MAI, Yuan F, Yin X, Lorkiewicz PK, Wei X, Feng W, McClain C, Zhang X.   +8 more
europepmc   +1 more source

Directing Zn Growth with Biased Adsorption of Straight‐chain Molecules for Superior Zn Anode Stability [PDF]

Fangfang Wu, Junkang Zhang, Lu Ma, Pengchao Ruan, Yulong Chen, Shibo Meng, Ruilian Yin, Wenhui Shi, Wenxian Liu, Jiang Zhou, Xiehong Cao   +10 more
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source