Results 61 to 70 of about 96,669 (282)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Emergent Ferroelectric Nematic and Heliconical Ferroelectric Nematic States in an Achiral “Straight” Polar Rod Mesogen

open access: yesAdvanced Science
Ferroelectric nematic liquid crystals (NFLCs) are distinguished by their remarkable polarization characteristics and diverse physical phenomena, sparking significant interest and excitement within the scientific community.
Hiroya Nishikawa   +6 more
doaj   +1 more source

Performance comparison of monoamides on U recovery by temperature swing extraction using Ce

open access: yesMechanical Engineering Journal
Nuclear fuel fabrication process has generated a large amount of wastes contaminated with enriched uranium, and those have been accumulated for long time in Japan.
Toshihiro IWAMOTO   +6 more
doaj   +1 more source

Theoretical studies on the pK~a~ values of perfluoroalkyl carboxylic acids: Chain helicity [PDF]

open access: yes, 2009
Semiempirical, ab initio, and density functional theory (DFT) studies were conducted on a homologous series of straight chain perfluoroalkyl carboxylic acids (PFCAs) ranging in chain length from C~1~ (trifluoroacetic acid; TFA) to C~9~ (perfluorodecanoic
Kaya Forest, Sierra Rayne
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Design and Research of Universal Chain Pre-pulling and Disassembling Device

open access: yesJixie chuandong, 2020
Aiming at the pre-stretching and disassembling link in chain manufacturing process, a universal device for pre-stretching and disassembling chain is designed.
Shukun Wang   +4 more
doaj  

Nonlinearity-induced conformational instability and dynamics of biopolymers

open access: yes, 2001
We propose a simple phenomenological model for describing the conformational dynamics of biopolymers via the nonlinearity-induced buckling and collapse (i.e. coiling up) instabilities.
  +18 more
core   +1 more source

A comparative assessment of octanol-water partitioning and distribution constant estimation methods for perfluoroalkyl carboxylates and sulfonates [PDF]

open access: yes, 2009
New experimental data is available in the literature regarding the octanol-water distribution behavior of representative straight chain perfluoroalkyl carboxylate (PFCA) and sulfonate (PFSA) congeners.
Kaya Forest, Sierra Rayne
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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