Results 81 to 90 of about 638,045 (294)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A comparative assessment of octanol-water partitioning and distribution constant estimation methods for perfluoroalkyl carboxylates and sulfonates [PDF]
, 2009 New experimental data is available in the literature regarding the octanol-water distribution behavior of representative straight chain perfluoroalkyl carboxylate (PFCA) and sulfonate (PFSA) congeners.
Kaya Forest, Sierra Rayne
core +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Journal of Lipid Research, 2003 Sterol carrier protein-2 (SCP-2) and SCP-x are ubiquitous proteins found in all mammalian tissues. Although both proteins interact with fatty acids, their relative contributions to the uptake, oxidation, and esterification of straight-chain (palmitic ...
Barbara P. Atshaves +2 more
doaj +1 more source
Undulations of a Straight Polymer Chain Embedded in a Membrane
Journal de Physique II, 1996 We consider a sinusoidal undulation of a straight, linear polymer embedded in a flat membrane exposed to a lateral tension. We determine the shape of the membrane and compute the elastic energy associated with the undulation of the polymer. Analysing this energy at different wavelengths of the undulation, we find the criteria of stability of the ...
Singh-Zocchi, M. +2 more
openaire +2 more sources
Dissipative shocks in a chain fountain
, 2014 The fascinating and anomalous behaviour of a chain that instead of falling straight down under gravity, first rises and then falls, acquiring a steady shape in space that resembles a fountain's sprinkle, has recently attracted both popular and academic ...
Virga, Epifanio G.
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Theoretical studies on the pK~a~ values of perfluoroalkyl carboxylic acids: Chain helicity [PDF]
, 2009 Semiempirical, ab initio, and density functional theory (DFT) studies were conducted on a homologous series of straight chain perfluoroalkyl carboxylic acids (PFCAs) ranging in chain length from C~1~ (trifluoroacetic acid; TFA) to C~9~ (perfluorodecanoic
Kaya Forest, Sierra Rayne
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source