Results 101 to 110 of about 6,718,270 (416)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Flexible strain sensors [PDF]

open access: yes, 2017
In one embodiment, a flexible strain sensor includes a flexible substrate having a top surface and a layer of piezoresistive amorphous carbon formed on the top surface of the substrate.Board of Regents, University of Texas ...
Chiao, Jung-Chih   +2 more
core   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

First-principles investigation of hydrogen adatoms on uniaxially strained graphene [PDF]

open access: yesarXiv, 2011
We have performed first-principles studies on adsorption patterns of hydrogen adatoms on uniaxially strained graphene. Our simulation reveals that the adsorption energy of adatoms are sensitive to the strain. Hydrogen adatoms on zigzag strained graphene tend to form a chain-like adsorption patterns perpendicular to the strain direction, but those under
arxiv  

Strain Modulation of Graphene by Nanoscale Substrate Curvatures: A Molecular View [PDF]

open access: yes, 2018
Spatially nonuniform strain is important for engineering the pseudomagnetic field and band structure of graphene. Despite the wide interest in strain engineering, there is still a lack of control on device-compatible strain patterns due to the limited understanding of the structure-strain relationship. Here, we study the effect of substrate corrugation
arxiv   +1 more source

Optimal time decay of the non cut-off Boltzmann equation in the whole space

open access: yes, 2012
In this paper we study the large-time behavior of perturbative classical solutions to the hard and soft potential Boltzmann equation without the angular cut-off assumption in the whole space $\threed_x$ with $\DgE$.
C. Mouhot   +28 more
core   +1 more source

Magnetic resonance imaging of myocardial strain after acute ST-segment-elevation myocardial infarction: a systematic review [PDF]

open access: yes, 2017
The purpose of this systematic review is to provide a clinically relevant, disease-based perspective on myocardial strain imaging in patients with acute myocardial infarction or stable ischemic heart disease.
Auger, Daniel A.   +4 more
core   +1 more source

Tunable intrinsic strain in two-dimensional transition metal electrocatalysts

open access: yesScience, 2019
Harnessing self-tuned strain Strain can modify the electronic properties of a metal and has provided a method for enhancing electrocatalytic activity. For practical catalysts, nanomaterials with high surface areas are needed.
Lei Wang   +8 more
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Straining for Perfection

open access: yesJournal of the American College of Cardiology, 2011
The hunt for optimal approaches to assessment of myocardial performance has been longstanding. However, assessment of segmental myocardial function lagged for decades and was largely qualitative and subjective, on the basis of endocardial excursion or wall thickening, not quantitative ...
openaire   +3 more sources

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