Results 41 to 50 of about 329,998 (301)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Paleotectonic residual strain energy in Southwest China
Geodesy and Geodynamics, 2015 Based on the orthotropic elastic theory of rock masses, the X-ray method was used to measure the distribution of macro-residual strain energy density along a depth profile, using core samples taken from 47 large-aperture deep boreholes in four regions of
Ou An
doaj +1 more source
Study on the Fractal Characteristics of the Pomegranate Biotite Schist under Impact Loading
Geofluids, 2021 In order to study the fractal characteristics of the pomegranate biotite schist under the effect of blasting loads, a one-dimensional SHPB impact test was carried out to test the dynamic compressive strength, damage morphology, fracture energy ...
Jianguo Wang +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Scientific ReportsResearch investigating the complex mechanical properties and energy evolution mechanisms of frozen calcareous clay under the influence of multiple factors is crucial for optimizing the artificial ground freezing method in shaft sinking, thereby enhancing
Jihao Feng +7 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The strain-energy-desity criterion - investigations for its applicability
, 2022 S.33-43 : Abb ...
Sommer, E. +2 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Temperature and strain scaling laws for the critical current density in Nb(_3)Sn and Nb(_3)Al conductors in high magnetic fields [PDF]
, 2001 Detailed, accurate measurements of critical current density and resistivity to determine the upper critical field have been made on a technological NbsAl conductor in magnetic fields up to 15 T, temperatures from 4.2 K up to the critical temperature and ...
Keys, Simon Alastair
core
Strain energy density relative to frequency.
, 2013 Strain energy density relative to frequency.
Zheng Wang (25883)
core +1 more source