Results 61 to 70 of about 8,865,343 (255)

Strain energy density approach for brittle fracture from nano to macroscale and breakdown of continuum theory [PDF]

open access: yes, 2021
In contrast to the great success at the macroscale, fracture mechanics theory fails to describe the fracture at a critical size of several nanometers due to the emerging effect of atomic discreteness with decreasing material size.
Shimada, Takahiro   +3 more
core   +1 more source

Study on the influence of elastic modulus heterogeneity on in-situ stress and its damage to gas shale reservoirs

open access: yesJournal of Natural Gas Geoscience, 2018
Shale heterogeneity has a significant effect on drilling and completions, hydraulic fracturing, as well as hydrocarbon development performance. However, it lacks representation of rock damage/failure caused by the mechanical heterogeneity and “stress ...
Daobing Wang   +6 more
doaj   +1 more source

Cyclic responses and microstructure sensitivity of Cr-based turbine steel under different strain ratios in low cycle fatigue regime

open access: yesMaterials & Design, 2021
When turbine steel services, i.e., startup and shutdown processes, the cyclic mechanical stress caused by the asymmetry loading conditions is introduced.
Xiufang Gong   +7 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Strain energy density relative to frequency.

open access: yes, 2013
Strain energy density relative to frequency.
Zheng Wang (25883)
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A review of the Energy Productivity Center's Least-Cost Energy Strategy study [PDF]

open access: yes, 1981
The Mellon Institute's Energy Productivity Center (EPC) has recently completed a study asking the question, "How would the nation have provided energy services in 1978 if its capital stock had een reconfigured to be optimal for actual 1978 energy prices?"
Manove, Michael   +2 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Calculation of crystallite sizes of pure and metals doped hydroxyapatite engaging Scherrer method, Halder-Wagner method, Williamson-Hall model, and size-strain plot

open access: yesResults in Materials
This research paper dealt with the synthesis and characterization of pure and metal-doped hydroxyapatite covering an in-depth crystallographic analysis.
Sanjana Afrin Disha   +3 more
doaj   +1 more source

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