Results 51 to 60 of about 1,453,733 (283)
Engineering Science and Technology, an International Journal, 2014 Strain measurement is important in mechanical testing. A wide variety of techniques exists for measuring strain in the tensile test; namely the strain gauge, extensometer, stress and strain determined by machine crosshead motion, Geometric Moire ...
H.B. Motra +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Data in Brief, 2019 Stress-strain curves in steady-state tension of aluminum 6061-T651 sourced from 9 lots of material from several manufacturers at 6 temperatures (20,100,150,200,250,300 °C) are presented.
B.S. Aakash +2 more
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Microsystems & Nanoengineering, 2022 Measurements of physiological parameters such as pulse rate, voice, and motion for precise health care monitoring requires highly sensitive sensors. Flexible strain gauges are useful sensors that can be used in human health care devices.
Sanghun Shin, Byeongjo Ko, Hongyun So
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Multilayered dynamic strain gauge using of piezoelectric PVDF films
MATEC Web of Conferences, 2017 The strain gauge made of a piezoelectric film is proposed. The operation of the gauge is based on the piezoelectric effect: the deformation of the gauge causes an electric potential proportional to the deformation.
Rogacheva Nelly
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source