Results 71 to 80 of about 1,453,733 (283)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 1938 This gauge was invented around 1938 at the National Bureau of Standards by mechanical engineer Herbert L. Whittemore. It was used to measure the elongation or contraction of a length on the surface of a structure such as a wall, column, or beam, thereby ...
Whittemore, Herbert L.
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Applied Bionics and Biomechanics, 2019 This study is aimed at providing an effective method for determining strain-load relationship and at quantifying the strain distribution within the whole tibia under axial compressive load on rats.
Jiazi Gao +4 more
doaj +1 more source
Strain measurement by oscillator circuit sensor using dummy gauge
Nihon Kikai Gakkai ronbunshu, 2015 The strain measurement system using a CMOS inverter oscillator circuit is simple and can be omit an amplifier because a counting device measures frequency changes of circuit voltage output caused by resistance changes of a strain gauge.
Takao UTSUNOMIYA +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Geometrical aspects of local gauge symmetry [PDF]
, 2004 This paper is an analysis of the geometrical interpretation of local gauge symmetry for theories of the Yang-Mills ...
Guay, Alexandre +1 more
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Force measurement using strain-gauge balance in a shock tunnel with long test duration
, 2016 Force tests were conducted at the long-duration-test shock tunnel JF12, which has been designed and built in the Institute of Mechanics, Chinese Academy of Sciences.
汪运鹏 +4 more
core +1 more source
Semiconductor strain sensor for measuring biaxial strain field
Nihon Kikai Gakkai ronbunshu, 2019 We developed a semiconductor strain sensor chip for measuring the biaxial strain with high sensitivity and low power consumption. This sensor chip has two bridge circuits (sensors) that consist of an impurity diffusion layer on a silicon substrate, and ...
Hiromi SHIMAZU +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source