Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Strain Sensing in Cantilever Beams Using a Tapered PMF with Embedded Optical Modulation Region
This paper presents the design of a strain-sensitive, dual ball-shaped tunable zone (DBT) taper structure for light intensity modulation. Unlike conventional tapered optical fibers, the DBT incorporates a central light field modulation zone within the ...
Xiaopeng Han +7 more
doaj +1 more source
Texture evaluation in warm deformation of an extruded Mg–6Al–3Zn alloy
To assess the effect of strain and strain rate on texture evolution of an extruded Mg–6Al–3Zn alloy, compression tests were carried out. Samples were prepared in the extrusion direction (ED) and normal direction (ND). The compression tests were performed
M. Kavyani +3 more
doaj +1 more source
Transverse Load Discrimination in Long-Period Fiber Grating via Artificial Neural Network
We present a general investigation of a Long-Period Grating (LPG) for transverse strain measurement. The transverse strain sensing characteristics, for instance, the load intensity and azimuthal angle, are analyzed with the data set generated by the LPG ...
F. O. Barino +2 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Two-dimensional semiconductors exhibit strong light emission under optical or electrical pumping due to quantum confinement and large exciton binding energies.
Shiqiao Qin +13 more
core +1 more source
Investigating the effect of Texture Intensity on the Forming Limit Diagram of Magnesium Microtubes used in Stents using Crystal Plasticity Finite Element Modeling [PDF]
Metal microtubes are usually made using the extrusion method, eventually creating a special texture in the tube. The way tissue is created in the microtube has a significant effect on its mechanical properties, which is very effective in the quality of ...
M. Reisi, A. Mirzakhani, A. Asempour
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
The Influence of Cyclic Loading on the Mechanical Properties of Well Cement
The cyclic loading generated by injection and production operations in underground gas storage facilities can lead to fatigue damage to cement sheaths and compromise the integrity of wellbores.
Zhen Zhang +7 more
doaj +1 more source
Light-Irradiation Wavelength and Intensity Changes Influence Aflatoxin Synthesis in Fungi
Fungi respond to light irradiation by forming conidia and occasionally synthesizing mycotoxins. Several light wavelengths, such as blue and red, affect the latter.
Tadahiro Suzuki
doaj +1 more source

