Results 131 to 140 of about 2,251,793 (347)

The Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Accepted Article.
Objective The aim of this systematic review was to synthesise the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye   +6 more
wiley   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

open access: yesAdvanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez   +8 more
wiley   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

open access: yesAdvanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang   +13 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

High-strain-rate superplasticity in oxide ceramics

open access: yesScience and Technology of Advanced Materials, 2007
Factors limiting the strain rate of superplastic deformation in ceramic materials are discussed on the basis of existing models and experimental results concerning high-temperature plastic deformation, intergranular cavitation and dynamic grain growth ...
Keijiro Hiraga, Byung-Nam Kim, Koji Morita, Hidehiro Yoshida, Tohru S. Suzuki and Yoshio Sakka
doaj  

A Dislocation based Constitutive Model for Warm Forming of Aluminum Sheet [PDF]

open access: yes, 2008
The formability of aluminum sheet can be improved considerably by increasing the temperature.\ud At elevated temperatures, the mechanical response of the material becomes strain rate dependent.\ud To accurately simulate warm forming of aluminum sheet, a ...
Boogaard, A.H. van den   +2 more
core   +1 more source

A rate theory of strain relaxation

open access: yesMaterials Science and Engineering, 1969
Abstract Dislocation mobility studies indicate that the symmetrical form of the energy barrier and the corresponding sinh expression, usually assumed in the analysis of strain relaxation, cannot be reconciled with the results obtained in dislocation velocity measurements.
openaire   +4 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

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