Results 101 to 110 of about 382,947 (255)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A multiscale approach for modeling crystalline solids [PDF]

, 2001
In this paper we present a modeling approach to bridge the atomistic with macroscopic scales in crystalline materials. The methodology combines identification and modeling of the controlling unit processes at microscopic level with the direct atomistic ...
Cuitiño, Alberto M., Goddard, William A., III, Ortiz, Michael, Stainier, Laurent, Strachan, Alejandro, Wang, Guofeng, Çağin, Tahir   +6 more
core  

A study of the static yield stress in a binary Lennard-Jones glass

, 2003
The stress-strain relations and the yield behavior of model glass (a 80:20 binary Lennard-Jones mixture) is studied by means of MD simulations. First, a thorough analysis of the static yield stress is presented via simulations under imposed stress ...
Berthier L., Bonn D., Chen L. J., Coussot P., Coussot P., Da Cruz F., David Lu C.-Y., Debrégeas G., F. Varnik, He G., Ho Huu C., J.-L. Barrat, L. Bocquet, Picard G., Pignon F., Rottler Jörg, van Aken B., Walls H. J.   +17 more
core   +3 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Strain rate dependency of laser sintered polyamide 12

EPJ Web of Conferences, 2015
Parts processed by Additive Manufacturing can now be found across a wide range of applications, such as those in the aerospace and automotive industry in which the mechanical response must be optimised.
Cook J.E.T., Goodridge R.D., Siviour C.R.   +2 more
doaj   +1 more source

Dynamics of Large-Scale Plastic Deformation and the Necking Instability in Amorphous Solids

, 2002
We use the shear transformation zone (STZ) theory of dynamic plasticity to study the necking instability in a two-dimensional strip of amorphous solid. Our Eulerian description of large-scale deformation allows us to follow the instability far into the ...
A. E. Lobkovsky, G. Gagnon, J. Aboudi, J. Lubliner, J. S. Langer, J. S. Langer, J. S. Langer, J. S. Langer, J. W. Hutchinson, L. O. Eastgate, L. Pechenik, L. Pechenik, L. E. Malvern, M. L. Falk, M. L. Falk, P. N. Brown, R. M. McMeeking, V. Tvergaard   +17 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Unraveling the temperature dependence of the yield strength in single-crystal tungsten using atomistically-informed crystal plasticity calculations

, 2015
We use a physically-based crystal plasticity model to predict the yield strength of body-centered cubic (bcc) tungsten single crystals subjected to uniaxial loading.
Ackermann, Alankar, Ali, Argon, Arieli, Arsenlis, Barton, Basinski, Bodner, Bowden, Brinckmann, Brunner, Brunner, Brünig, Bulatov, Bulatov, Cai, Caillard, Caillard, Caillard, Cereceda, Cereceda, Chang, Chaussidon, Chen, Christensen, Christian, Dao, David Cereceda, Deo, Dezerald, Dezerald, Dierk Raabe, Dorn, Drucker, Duesbery, Duesbery, Duesbery, Dumoulin, Erieau, Escaig, Escaig, Estrin, Fish, Franciosi, Franciosi, Franciosi, Franz Roters, Gilbert, Gordon, Gröger, Gröger, Gröger, Gröger, Gröger, Gupta, Hamelin, Hedworth, Henkelman, Hull, Hutchinson, Hölscher, Hölscher, Ito, J. Manuel Perlado, Jaime Marian, Kalidindi, Kitayama, Klopp, Knezevic, Kocks, Koester, Komanduri, Kuchnicki, Lee, Lee, Li, Lim, Lim, Lim, Lin, Lubliner, Ma, Madec, Marichal, Marichal, Martin Diehl, McDowell, Mecking, Monnet, Monnet, Naamane, Narayanan, Pariseau, Patra, Peeters, Pichl, Plimpton, Prager, Proville, Qin, Queyreau, Queyreau, Raabe, Raabe, Raabe, Raffo, Raphanel, Reina, Romaner, Roters, Roters, Roters, Samolyuk, Scarle, Schmid, Seeger, Seeger, Serenelli, Sheng, Sherwood, Soare, Stainier, Starovoitov, Stephens, Stukowski, Swinburne, Takeuchi, Tang, Taylor, Taylor, Taylor, Taylor, Ventelon, Ventelon, Vitek, Vitek, Weinberger, Weinberger, Woodward, Wurster, Yalcinkaya, Yang, Zurek, Zwiesele, Šesták   +145 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source