Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The effect of strain rate on compressive behavior and failure mechanism of CMDB propellant
Defence Technology, 2022 The compressive mechanical behavior of composite modified double base (CMDB) propellant was investigated across a wide scope of strain rates ranging from 10−3 s−1 to 4210 s−1 at room temperature, by applying a conventional universal testing machine and a
Heng-ning Zhang +4 more
doaj +1 more source
Relaxation oscillations and negative strain rate sensitivity in the Portevin - Le Chatelier effect
, 2000 A characteristic feature of the Portevin - Le Chatelier effect or the jerky flow is the stick-slip nature of stress-strain curves which is believed to result from the negative strain rate dependence of the flow stress.
A. Arneodo +35 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Direct FE2 for simulating strain-rate dependent compressive failure of cylindrical CFRP
Composites Part C: Open Access, 2021 In this study, the strain-rate dependent compressive failure of cylindrical carbon fiber reinforced plastics (CFRP) is simulated by using Direct FE2.
Jun Koyanagi +4 more
doaj +1 more source
Stress measurements in the earth's crust - recrystallized grain size piezometry revisited [PDF]
, 2012 EGU2012-13016 The dynamically recrystallized grain size is the most reliable paleo-piezometer to determine the differential stress in the Earth’s crust and mantle.
Stipp, Michael
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Initiation and Mechanisms of Plasticity in Bimetallic Al-Cu Composite
Metals, 2023 We studied the shear deformation of a laminar Al-Cu composite with (100) and (110) interfaces with a shear perpendicular to the lamellae in comparison with pure single crystal Al and Cu at strain rates of 109 s−1 and 108 s−1 and different initial ...
Vasiliy S. Krasnikov, Alexander E. Mayer
doaj +1 more source
Literature study report of plasticity induced anisotropic damage modeling for forming processes [PDF]
, 2009 A literature study report covering the topics; micromechanics of damage, continuum damage mechanics (gurson model and effective variable concept) and the dependence of damage on strain rate and ...
Niazi, M.S.
core +1 more source
Rate Dependence and Role of Disorder in Linearly Sheared Two-Dimensional Foams
, 2008 The shear flow of two dimensional foams is probed as a function of shear rate and disorder. Disordered foams exhibit strongly rate dependent velocity profiles, whereas ordered foams show rate independence.
D. Weaire +3 more
core +1 more source