Results 31 to 40 of about 517,545 (268)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Unveiling the Strain Rate Sensitivity of G18NiCrMo3-6 CAST Steel in Tension/Compression Asymmetry

open access: yesApplied Sciences, 2023
This research was devoted to unveiling the strain rate sensitivity (SRS) of G18NiCrMo3-6 cast steel in tension/compression asymmetry. For that purpose, detailed mechanical characterization tests were conducted providing a process window covering quasi ...
Barış Çetin   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Mechanical properties and strain rate sensitivity of 3D laserdeposited Ti-6Al-4V alloy

open access: yesEPJ Web of Conferences, 2018
Ti-6Al-4V has become the most common material in titanium alloy. Due to High specific strength, low density and excellent mechanical properties, it has been used in not only living, sports goods but also aerospace, defense industries.
Woo Sanghyun, Lee Yerim, Park Leeju
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Effects of the Strain Rate Sensitivity and Strain Hardening on the Saturated Impulse of Plates

open access: yesLatin American Journal of Solids and Structures
This paper studies the stiffening effects of the material strain rate sensitivity and strain hardening on the saturated impulse of elastic, perfectly plastic plates.
Ling Zhu, Xu He, F. L. Chen, Xueyu Bai
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

FORMABILITY OF AUSTENITIC STAINLESS STEEL 316 SHEET IN DYNAMIC STRAIN AGING REGIME

open access: yesActa Metallurgica Slovaca, 2014
Dynamic strain aging region for austenitic stainless steel 316 was investigated from room temperature to 650°C at constant strain rates of 1x10-2, 1x10-3 and 1x10-4 sec-1.
Syed Mujahed Hussaini   +2 more
doaj   +1 more source

Effect of Annealing on Strain Rate Sensitivity of Metallic Glass under Nanoindentation

open access: yesMetals, 2020
The influence of isothermal annealing on the strain rate sensitivity (SRS) of a Zr-based bulk metallic glass (BMG) was investigated by nanoindentation. A more positive SRS is observed with a decrease in the content of the free volume (FV) of the sample ...
Mingcan Li
doaj   +1 more source

Home - About - Disclaimer - Privacy