Results 151 to 160 of about 812,407 (248)

Rapid in situ RNA imaging based on Cas12a thrusting strand displacement reaction. [PDF]

open access: yesNucleic Acids Res, 2023
Cheng X   +14 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Four-Analog Computation Based on DNA Strand Displacement

open access: yesACS Omega, 2017
Chengye Zou   +5 more
doaj   +1 more source

Low‐Intensity Focused Ultrasound Enables Temporal Modulation of Human Midbrain Organoid Differentiation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that low‐intensity ultrasound stimulation enables temporal modulation of midbrain organoid differentiation using a modular multi‐well stimulation platform. In particular, we show that ultrasound promotes the proliferation of dopaminergic progenitor cells.
Jinseong Jeong   +8 more
wiley   +1 more source

Optimization of SWCNT-FET Biosensors by Aptamer Engineering and Toehold-Mediated Strand Displacement. [PDF]

open access: yesAdv Sci (Weinh)
Miao H   +8 more
europepmc   +1 more source

Toehold clipping: A mechanism for remote control of DNA strand displacement. [PDF]

open access: yesNucleic Acids Res, 2023
Faheem H   +7 more
europepmc   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

open access: yesAdvanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang   +6 more
wiley   +1 more source

Pol γ possesses separate metal binding sites for polymerase and strand displacement functions. [PDF]

open access: yesNucleic Acids Res
Baruch-Torres N   +8 more
europepmc   +1 more source

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