Results 1 to 10 of about 3,903,533 (154)

A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs

Pharmaceuticals, 2022
The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particular ...
Maria Noelia Chao, Jean-Michel Chezal, Eric Debiton, Damien Canitrot, Tiffany Witkowski, Sophie Levesque, Françoise Degoul, Sébastien Tarrit, Barbara Wenzel, Elisabeth Miot-Noirault, Audrey Serre, Aurélie Maisonial-Besset   +11 more
doaj   +1 more source

Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the ⁶⁴Cu-Labelling of Immunoconjugates

Molecules, 2022
The development of 64Cu-based immuno-PET radiotracers requires the use of copper-specific bifunctional chelators (BFCs) that contain functional groups allowing both convenient bioconjugation and stable copper complexes to limit in vivo bioreduction ...
Aurélie Maisonial-Besset, Tiffany Witkowski, Mercedes Quintana, Sophie Besse, Vincent Gaumet, Axel Cordonnier, Cyrille Alliot, Aurélien Vidal, Caroline Denevault-Sabourin, Sébastien Tarrit, Sophie Levesque, Elisabeth Miot-Noirault, Jean-Michel Chezal   +12 more
doaj   +1 more source

Interest and Limits of [18F]ML-10 PET Imaging for Early Detection of Response to Conventional Chemotherapy

Frontiers in Oncology, 2021
One of the current challenges in oncology is to develop imaging tools to early detect the response to conventional chemotherapy and adjust treatment strategies when necessary.
Elodie Jouberton, Elodie Jouberton, Sébastien Schmitt, Aurélie Maisonial-Besset, Emmanuel Chautard, Emmanuel Chautard, Frédérique Penault-Llorca, Frédérique Penault-Llorca, Florent Cachin, Florent Cachin   +9 more
doaj   +1 more source

RFID trial: localization of non-palpable breast lesions using radiofrequency identification tags or wire

BMC Cancer, 2023
Background Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women. Approximately 50% of breast cancers are discovered at an early stage in patients for whom conservative surgery is indicated.
Hugo Veyssiere, Margot Dressaire, Raphaël Pete, Céleste Pinard, Ioana Molnar, Catherine Abrial, Angeline Ginzac, Xavier Durando, Marielle Tekath   +8 more
doaj   +1 more source

Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa

Microbiology Spectrum, 2022
Pf4 is a filamentous bacteriophage integrated as a prophage into the genome of Pseudomonas aeruginosa PAO1. Pf4 virions can be produced without killing P. aeruginosa. However, cell lysis can occur during superinfection when Pf virions successfully infect
Damien Tortuel, Ali Tahrioui, Audrey David, Mélyssa Cambronel, Flore Nilly, Thomas Clamens, Olivier Maillot, Magalie Barreau, Marc G. J. Feuilloley, Olivier Lesouhaitier, Alain Filloux, Emeline Bouffartigues, Pierre Cornelis, Sylvie Chevalier   +13 more
doaj   +1 more source

Cotton and Flax Textiles Leachables Impact Differently Cutaneous Staphylococcus aureus and Staphylococcus epidermidis Biofilm Formation and Cytotoxicity

Life, 2022
Bacteria can bind on clothes, but the impacts of textiles leachables on cutaneous bacteria remain unknown. Here, we studied for the first time the effects of cotton and flax obtained through classical and soft ecological agriculture on the ...
Chloé Catovic, Imen Abbes, Magalie Barreau, Catherine Sauvage, Jacques Follet, Cécile Duclairoir-Poc, Anne Groboillot, Sandra Leblanc, Pascal Svinareff, Sylvie Chevalier, Marc G. J. Feuilloley   +10 more
doaj   +1 more source

[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

EJNMMI Research, 2020
Purpose Pathological complete response to the neoadjuvant therapy (NAT) for triple negative breast cancer (TNBC) is predictive of prolonged patient survival.
Elodie Jouberton, Sébastien Schmitt, Emmanuel Chautard, Aurélie Maisonial-Besset, Marie Roy, Nina Radosevic-Robin, Jean-Michel Chezal, Elisabeth Miot-Noirault, Yann Bouvet, Florent Cachin   +9 more
doaj   +1 more source

Se jouer des frontières du marché : stratégies résidentielles des classes moyennes autour de l’agglomération lilloise

Lien Social et Politiques, 2021
Partant du constat que les espaces frontaliers restent trop peu étudiés par les sociologues de l’urbain, cet article analyse les stratégies résidentielles de différentes fractions des classes moyennes originaires de l’agglomération lilloise et ayant ...
Garance Clément
doaj   +1 more source

FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

Journal of Neuroinflammation, 2019
Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune-mediated inflammatory disease of the peripheral nervous system characterized by a response directed against certain myelin proteins and for which therapies are ...
Laurent Kremer, Omar Taleb, Nelly Boehm, Ayikoe Guy Mensah-Nyagan, Elisabeth Trifilieff, Jérôme de Seze, Susana Brun   +6 more
doaj   +1 more source

5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

Acta Neuropathologica Communications, 2018
Serotoninergic activation which decreases brain Aβ peptides is considered beneficial in mouse models for Alzheimer’s disease (AD), but the mechanisms involved remain unclear.
Christian Klein, Guy Roussel, Susana Brun, Cristina Rusu, Christine Patte-Mensah, Michel Maitre, Ayikoe-Guy Mensah-Nyagan   +6 more
doaj   +1 more source