Results 1 to 10 of about 3,715,109 (206)

A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs

open access: yesPharmaceuticals, 2022
The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particular ...
Maria Noelia Chao   +11 more
doaj   +1 more source

Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the 64Cu-Labelling of Immunoconjugates

open access: yesMolecules, 2022
The development of 64Cu-based immuno-PET radiotracers requires the use of copper-specific bifunctional chelators (BFCs) that contain functional groups allowing both convenient bioconjugation and stable copper complexes to limit in vivo bioreduction ...
Aurélie Maisonial-Besset   +12 more
doaj   +1 more source

Interest and Limits of [18F]ML-10 PET Imaging for Early Detection of Response to Conventional Chemotherapy

open access: yesFrontiers in Oncology, 2021
One of the current challenges in oncology is to develop imaging tools to early detect the response to conventional chemotherapy and adjust treatment strategies when necessary.
Elodie Jouberton   +9 more
doaj   +1 more source

RFID trial: localization of non-palpable breast lesions using radiofrequency identification tags or wire

open access: yesBMC Cancer, 2023
Background Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women. Approximately 50% of breast cancers are discovered at an early stage in patients for whom conservative surgery is indicated.
Hugo Veyssiere   +8 more
doaj   +1 more source

Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa

open access: yesMicrobiology Spectrum, 2022
Pf4 is a filamentous bacteriophage integrated as a prophage into the genome of Pseudomonas aeruginosa PAO1. Pf4 virions can be produced without killing P. aeruginosa. However, cell lysis can occur during superinfection when Pf virions successfully infect
Damien Tortuel   +13 more
doaj   +1 more source

[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

open access: yesEJNMMI Research, 2020
Purpose Pathological complete response to the neoadjuvant therapy (NAT) for triple negative breast cancer (TNBC) is predictive of prolonged patient survival.
Elodie Jouberton   +9 more
doaj   +1 more source

Épreuve et argumentation dans les discours panafricanistes : stratégies d’une (con)quête en questionnement

open access: yesAltralang Journal, 2022
Test and Argumentation in Pan-Africanist Discourses: Strategies of A Questioning Conquest ABSTRACT: Discourses are the expression of a certain activity, like stories.
Hamidou BELEM
doaj   +1 more source

FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis

open access: yesJournal of Neuroinflammation, 2019
Background Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune-mediated inflammatory disease of the peripheral nervous system characterized by a response directed against certain myelin proteins and for which therapies are ...
Laurent Kremer   +6 more
doaj   +1 more source

Des circuits courts à la sécurité sociale de l’alimentation : économies concrètes et récit politique pour la solidarité alimentaire

open access: yesLien Social et Politiques, 2023
Les inégalités d’accès à une alimentation de qualité sont un marqueur des sociétés contemporaines. En les confirmant, la crise de la COVID-19 a aussi donné plus de visibilité aux initiatives de solidarité alimentaire visant à réduire ces inégalités, en s’
Yuna Chiffoleau   +3 more
doaj   +1 more source

5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

open access: yesActa Neuropathologica Communications, 2018
Serotoninergic activation which decreases brain Aβ peptides is considered beneficial in mouse models for Alzheimer’s disease (AD), but the mechanisms involved remain unclear.
Christian Klein   +6 more
doaj   +1 more source

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