Results 21 to 30 of about 3,903,632 (253)

Tumor sink effect on melanin-ligand [131I]ICF01012 in melanoma and its implications for targeted radionuclide therapy

EJNMMI Research
Background The tumor sink effect refers to the sequestration of a radiopharmaceutical compound by tumors, leading to a reduced bioavailability in non-target organs and potential alterations in radiopharmaceuticals distribution.
Elodie Jouberton, Sophie Besse, Tommy Billoux, Philippe Auzeloux, Sébastien Schmitt, Jean-Michel Chezal, Nicolas Sas, Laurine Noirault, Manon Auriol, Sophie Levesque, Marine Delmas, Benjamin Chaussin, Emmanuel Chautard, Elisabeth Miot-Noirault, Jacques Rouanet, Florent Cachin   +15 more
doaj   +1 more source

Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Aortic stenosis due to deleterious remodeling of the aortic valve is a health concern since it can be corrected only by valve replacement due to the poor knowledge of cellular mechanisms involved. Fibroblastic valvular interstitial cells (VICs)
Margaux Aize, Arthur Boilève, Benoit D. Roussel, Laura Brard, Harlyne Mpweme Bangando, Corentin Kerevel, Alexandre Lebrun, Hind Messaoudi, Vladimir Saplacan, Alain Manrique, Romain Guinamard, Christophe Simard   +11 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

A crise financeira de 2008: os discursos e as estratégias do governo e dos fundos de pensão

Dados: Revista de Ciências Sociais, 2013
Dans cet article, on examine la crise commencée en 2008. Sous l'inspiration des travaux de Lebaron (2010; 2011) et Grun (2010), on essaie de saisir la "dimension cognitive" de la crise, à travers les discours produits (et reproduits) par des membres du ...
Maria Chaves Jardim
doaj   +1 more source

LA PROBLÉMATIQUE DE LA MORTALITÉ MATERNELLE AU CONGO : ANALYSE ET ASPECTS JURIDIQUES [PDF]

Cahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2023
Au Congo, la nécessité d’un cadre juridique protecteur de la femme enceinte est une préoccupation. En effet, le risque que court une femme de mourir ou de devenir invalide durant la grossesse et l’accouchement est en rapport étroit avec son statut social
Maître Hygin Didace AMBOULOU
doaj  

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Etude Sur la Stratégie et le Programme D'appui à la Société Civile Burundaise [PDF]

, 2002
The author study's strategies and programs to build civil society in ...
Christophe Sebudandi, Gérard Nduwayo
core  

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Seed-div: an abstract role-playing game for discussing collective management of agrobiodiversity [PDF]

, 2010
L'objectif principal de cette recherche est d'accompagner les paysans dans l'élaboration d'un cadre de gestion collective de la diversité de leurs variétés de céréales vivrières.
Abrami, Géraldine, Bazile, Didier, Bousquet, François, Coulibaly, Harouna   +3 more
core   +1 more source