Results 101 to 110 of about 11,186,117 (295)

Shared geriatric mental health care in a rural community [PDF]

, 2007
Introduction: A pilot project in shared mental health care was initiated to explore opportunities to increase the capacity of the rural primary care system as a resource for older people with mental health needs.
Dolansky, D, Le Clair, JK, Leon, S, Parenteau, P, Sullivan, MP   +4 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Setting up and management of public policies multifunctional purpose. The case of Developing Countries : Capitalisation of research results on the multifunctionality of agriculture and rural areas [PDF]

, 2005
The notion of multifuncionality appeared for the first time in 1992 in the proceedings of the International Conference of the United Nations on Environment and Development.
Bonnal, Philippe, Losch, Bruno, Van Vliet, Geert   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Towards development of a report on the state of the world's forest genetic resources [PDF]

, 2008
La disponibilité de données fiables est indispensable pour la conservation efficace et la gestion durable des ressources génétiques forestières. À ce jour, il n'existe aucune vision globale de l'état et de l'évolution de ces ressources, ni d'estimations ...
Palmberg-Lerche, Christel, Souvannavong, Oudara   +1 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Opportunities for classical biological control of weeds in European overseas territories [PDF]

, 2008
European overseas territories are home to biodiversity and endemism of worldwide importance, vastly superior to that of continental Europe as a whole. They are, however, much more threatened by invasive species, including hundreds of alien invasive plant
Baret, Stéphane, Blanfort, Vincent, Lavergne, Christophe, Le Bourgeois, Thomas, Meyer, Jean-Yves, Soubeyran, Yohann   +5 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Stratégies de femmes entrepreneures dans les oasis de Ghardaïa en Algérie : s’adapter à un contexte patriarcal et saisir de nouvelles opportunités économiques

Cahiers Agricultures
Au Maghreb, les femmes entrepreneures font face à de nombreuses contraintes économiques, sociales et culturelles. Ces contraintes, identifiées dans de nombreuses études, limitent souvent fortement la capacité des femmes à initier leur projet d ...
Bouzid Amel, Hamamouche Meriem Farah, Faysse Nicolas   +2 more
doaj   +1 more source