Results 101 to 110 of about 3,903,632 (253)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

New options for pest management in horticultural crop-based agroecosystems of Sudano-Sahelian Africa in the climate change context [PDF]

open access: yes, 2011
In the climate change context, ICRISAT is promoting water-saving cropping systems mixing food and horticultural crops for the Sudano-Sahelian zone of Western Africa. ICRISAT's partners in Niger (CIRAD, the University of Niamey and INRAN) are seeking ways
Fatondji, Dougbedji   +9 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Remittances as a Social Status Signaling Device [PDF]

open access: yes
L'article étudie les transferts des migrants en tant que moyen pour signaler leur situation économique aux yeux des résidents. En information imparfaite, les migrants pauvres peuvent transférer plus que normal, pour se faire passer pour des migrants ...
Claire Naiditch, Radu Vranceanu
core  

L'utilisation des moteurs de recherche par les jeunes : Impact des connaissances du domaine et des connaissances procédurales sur les stratégies d'exploration visuelle [PDF]

open access: yes, 2010
International audienceDans une expérimentation conduite avec 53 élèves de CM2 utilisant la technique de l'oculométrie, nous tentons de mieux comprendre les stratégies d'exploration visuelle utilisées par de très jeunes usagers lors d'une tâche de ...
Chanquoy, Lucile   +7 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Stratégies de femmes entrepreneures dans les oasis de Ghardaïa en Algérie : s’adapter à un contexte patriarcal et saisir de nouvelles opportunités économiques

open access: yesCahiers Agricultures
Au Maghreb, les femmes entrepreneures font face à de nombreuses contraintes économiques, sociales et culturelles. Ces contraintes, identifiées dans de nombreuses études, limitent souvent fortement la capacité des femmes à initier leur projet d ...
Bouzid Amel   +2 more
doaj   +1 more source

Taxing the urban unrecorded economy in sub-Saharan Africa [PDF]

open access: yes
The global public revenue level of numerous African countries is low and the tax burden is highly concentrated on modern sector firms. One of the most current explanations for the low level of public revenue is the under-taxation of the urban unrecorded ...
Catherine ARAUJO BONJEAN   +1 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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