Results 231 to 240 of about 182,784 (297)

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

open access: yesAdvanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang   +9 more
wiley   +1 more source

Volcano‐Inspired Dual‐Carbon Network Aerogel for High‐Performance Solar Evaporation With Edge‐Directed Salt Crystallization and Recovery

open access: yesAdvanced Science, EarlyView.
A volcano‐inspired dual‐carbon aerogel featuring hierarchical conduits and an outer carbon‐fiber shell directs rapid water transport, confines heat, and enables directional salt migration. Radial temperature gradients in the conical structure trigger Marangoni‐driven edge‐localized salt crystallization while maintaining an unobstructed photothermal ...
Shuyue Feng   +8 more
wiley   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

The Elephant Trunk Skin Inspires a Highly Sensitive and Deformable, Yet Robust, Armor Skin

open access: yesAdvanced Science, EarlyView.
The study presents the elephant trunk‐inspired armor skin with tactile sensing (ETATS). The ETATS architecture stretches and compresses while resisting puncture and tear, and it enables optical detection of pressure and lateral strain. Morphology‐based decoupling of strain and pressure paves the way to sensitive and deformable, yet robust, soft‐robotic
Jun Chang Yang   +3 more
wiley   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

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