Results 111 to 120 of about 23,258,662 (303)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Strategic analysis of body composition indices and resting platelet ATP levels in professional soccer players for better platelet-rich plasma therapy. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Ushiki T   +9 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Regional Strategic Analysis and Knowledge Support System (ReSAKSS)

open access: yes
Regional strategic analysis and knowledge support system (ReSAKSS) is a Africa-focused database nodes that compile, analyze, and disseminate data, information, and tools to help design, implement, monitor, and evaluate rural development ...
The Regional Strategic Analysis and Knowledge Support System
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

APPLICATION OF INFORMATION AND COMMUNICATION TECHNOLOGIES FOR THE CONTROL OF THE TECHNICAL STATE OF VEHICLES IN A TRANSPORT STREAM

open access: yesЦифровая трансформация, 2018
The article deals with the specifics of the application of information technologies in the transport sphere. The importance of improving the safety of the vehicle operation is substantiated, and possible ways of solving this issue are presented.
N. S. Jankevich
doaj   +2 more sources

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