Results 131 to 140 of about 23,258,662 (303)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Morocco 1943

, 1943
"No. 1131, January, 1943." "Restricted (supersedes edition of October 7, 1942)." Gift from Office of Strategic Services -- Aug 1945.B ...
United States. Office of Strategic Services. Research and Analysis Branch
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Cost-effectiveness and alternatives to the B-1 strategic bomber / Ron Huisken.

, 1979
Includes bibliographical references.On 30 June 1977, President Carter announced that the United States would not proceed with production and deployment of the B-l strategic bomber.
Huisken, Ronald Herman
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Strategic Innovation Assets voor Nederland

, 2019
Deze studie over Strategic Innovation Assets geeft een aanzet voor het identificeren van innovatie assets die een ‘kritische’ rol vervullen voor de toekomstige welvaart van Nederland.
Bakker, B.J.
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Structure and Trend Analysis of Strategic Management Subject Networks in Iran (Case Study: Strategic Management Journals) [PDF]

, 2019
Investigation of the number and diversity of articles in the field of strategic management in recent years shows that this field is one of the most favorite and well-considered areas.
Amirhossein Tayebi Abolhasani, Shahin Rouhanirad   +1 more
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Exploring search strategy for systematic literature review: evidence from the International Journal of Management Reviews

Business: Theory and Practice
Systematic literature reviews (SLRs) advance management theory and practice by synthesizing knowledge in a structured and transparent manner. However, inconsistent reporting of search strategies limits replicability and methodological rigor.
Marek Szarucki, Andriejus Sadauskis, Alma Mačiulytė-Šniukienė, Oskar Kosch   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

An institutional analysis of strategic posture

, 2008
[Abstract]: This paper investigates the role of formal and informal institutions in shaping the strategic posture of mico, small, and medium enterprises (MSMEs).
Roxas, Banjo G.
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