Results 131 to 140 of about 2,661,182 (351)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

APPLICATION OF INFORMATION AND COMMUNICATION TECHNOLOGIES FOR THE CONTROL OF THE TECHNICAL STATE OF VEHICLES IN A TRANSPORT STREAM

open access: yesЦифровая трансформация, 2018
The article deals with the specifics of the application of information technologies in the transport sphere. The importance of improving the safety of the vehicle operation is substantiated, and possible ways of solving this issue are presented.
N. S. Jankevich
doaj   +2 more sources

Digital Diplomacy: The Impact of Technology on Modern Diplomacy and Foreign Policy. Current Realities and Future Prospects [PDF]

open access: yesRomanian Journal of European Affairs
The paper examines how digital technologies are changing the field of diplomacy. It looks at how diplomacy has evolved from traditional practices to a modern form where technology is essential. The paper covers various digital tools, such as social media,
Carola Frey
doaj  

Rapid Budget Analysis of the Agricultural Sector for the General Budget Support Annual Review 2010/11. [PDF]

open access: yes
The main objective of the budget analysis chapter is to provide an overall assessment of how well the approved budget allocations in 2010-11 align with the strategic objectives and with sector strategic priorities of the Second National Strategy for ...
Francken, Nathalie, Zorya, S
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Strategic analysis of petty corruption: Entrepreneurs and bureaucrats [PDF]

open access: yes
This paper develops a game-theoretic model of "petty corruption" by government officials. Such corruption is widespread, especially (but not only) in developing and transition economies.
Ariane Lambert-Mogiliansky   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

TENDENCIES OF DEVELOPMENT OF SMALL INNOVATIVE ENTREPRENEURSHIP AS ONE OF THE MAIN INSTITUTES OF THE NATIONAL INNOVATION SYSTEM OF THE REPUBLIC OF BELARUS

open access: yesЦифровая трансформация, 2018
Features of small innovative entrepreneurship as the intellectual intermediary between a science and manufacture are considered. Trends in the development of small innovative entrepreneurship in the Republic of Belarus, as well as trends in the ...
A. A. Kosenko
doaj   +2 more sources

Strategic and Administrative Human Resource Management (HRM): A Study of HRM Reporting in Entrepreneurial Firms [PDF]

open access: yes, 1998
This paper reports the results of an exploratory study examining firm characteristics associated with choosing an administrative or strategic approach to HRM.
Welbourne, Theresa M.
core   +1 more source

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