Results 91 to 100 of about 1,083,939 (284)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Frontiers in EducationBackgroundDeep learning (DL), a subset of machine learning and artificial intelligence (AI), is transforming engineering by addressing complex problems with innovative solutions.
Arianna G. Tobias, Javeed Kittur
doaj +1 more source
Maintaining technical excellence requires a national plan [PDF]
To meet the challenge of technical excellence, AIA established a rocket propulsion committee to develop the National Rocket Propulsion Strategic Plan. Developing such a plan required a broad spectrum of experience and disciplines. The Strategic Plan team
Davidson, T. F.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Dominance-Solvable Lattice Games [PDF]
This paper derives sufficient and necessary conditions for dominance-solvability of so-called lattice games whose strategy sets have a lattice structure while they simultaneously belong to some metric space.
Zimper, Alexander
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
LOJİSTİK YÖNETİMİNDE ÇEVRESEL DEĞİŞİMLER BAĞLAMINDA STRATEJİK UYGULAMALAR
Sosyal Ekonomik Araştırmalar Dergisi, 2010 Organizasyonlar genel olarak piyasada, ekonomide, toplumda, çevrede, siyasette, veya spesifik olarak hizmet alanında, finans piyasalarında, tedarikçilerde oluşan herhangi bir değişime direk veya direk olmayan yollardan maruz kalırlar.
Ruhet Genç
doaj +4 more sources
Special Issue on the Third Mediterranean Photonics Conference (MePhoCo2014)
IEEE Photonics Journal, 2014 In general, the papers in this special issue focus on recent advances, including modeling, development, and fabrication strategies, as well as applications in strategic sectors, such as the case of safety and security field trials.
Mario N. Armenise +3 more
doaj +1 more source
The Strategic Role of Marketing Communication in he SME: the Case of Fornari SpA [PDF]
In this paper we discuss the strategic importance of communication and Intranet for theItalian Small and Medium Enterprise (SMEs). We analyse the case of Fornari SpA, an Italian medium size clothing and shoes manufacturer that uses internet as a ...
Andrea Buratti, Marco Cioppi
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source