Results 111 to 120 of about 1,083,939 (284)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A beautiful theory [PDF]

open access: yes
It wasn’t A Beautiful Mind—the book or the movie—that made John Forbes Nash, Jr., famous. It was his work in game theory, a theory that models strategic interactions between people as games.
Ed Nosal, Peter Rupert
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Towards a new theory of economic policy: Continuity and innovation [PDF]

open access: yes
This paper outlines the evolution of the theory of economic policy from the classical contributions of Frisch, Hansen, Tinbergen and Theil to situations of strategic interaction.
Acocella Nicola, Di Bartolomeo Giovanni
core  

Model Strategic Planning for Information System Pada Amik AMIKOM Cipta Darma Surakarta [PDF]

open access: yes, 2015
The main emphasis of the strategic planning of information is how to use technology appropriately to help the College in order to increase profits, encourage the growth of the company and won the competition with its competitors without forgetting ...
Marco, R. (Robert)
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Characterizing Stability Properties in Games with Strategic Substitutes [PDF]

open access: yes
In games with strategic substitutes (GSS), convergence of the best response dynamic starting from the inf (or sup) of the strategy space is equivalent to global stability (convergence of every adaptive dynamic to the same pure strategy Nash equilibrium).
Sunanda Roy, Tarun Sabarwal
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Game Theory in Strategic Management-Dynamic Games. Theoretical and Practical Examples

open access: yesManagement Dynamics in the Knowledge Economy, 2018
Game Theory provides an analysis tool for describing the decision-making process of one or more players, their behavior when there are plenty of possible outcomes.
Mihail BUSU
doaj  

Employing Artificial Intelligence Applications and Their Implications for Developing the Saudi Sports System

open access: yesScientific Journal of King Faisal University: Humanities and Management Sciences
This study aims to explore the reality of employing artificial intelligence (AI) applications and their impact on the development of the Saudi sports system.
Wael Abdel Raouf Khalifa
doaj   +1 more source

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