Results 171 to 180 of about 107,402 (262)

Strategic Implementation of Multimaterial Additive Manufacturing: Bridging Research and Real-World Applications

ACS Omega
Jigar Patadiya, Balasubramanian Kandasubramanian, Sreenivasan Sreeram, Priyanka Deelip Patil, Rihan Mujawar, Amol Indalkar, Mohamed Kchaou, Faisal Khaled Aldawood   +7 more
doaj   +1 more source

Building a Science-Driven Business: How National Institutes of Health Funding Enabled an Evidence-Based Approach to Maternal Mental Health Innovation. [PDF]

JMIR Form Res
Huberty J, Baez L, McAlister K, Kerppola M.   +3 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Ecosystem simulation: the software to platform leap. [PDF]

Sci Rep
Liu Z, Cui Y, Zhang Y, Li Z, Liu X, Wang S.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The strategic trajectory of artificial intelligence in Qatar's healthcare sector: a model for UN Sustainable Development Goal 9. [PDF]

Front Artif Intell
Ismail MA.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Strategic Prioritization of Mining Policies in Colombia Through The IGOR Hybrid Framework. [PDF]

Environ Manage
Jaramillo-Álvarez P, Smith R, Berrio-Giraldo L, Araque-Mendoza OT, Correa-Florez CA, Arango-Aramburo S.   +5 more
europepmc   +1 more source