Results 81 to 90 of about 1,083,939 (284)

Strategic Risk Management: Application to Manufacturing [PDF]

open access: yesThe Open Industrial & Manufacturing Engineering Journal, 2010
Existing risk management methods have a tendency to be focussed on the threats (rather than the opportunities) and the technology risk (rather than the organisational features of the problem). Also, they are better developed for quanti- tative variables and where mathematically precise problem-representation exists than qualitative variables and where ...
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Five key strategic priorities of integrating patient generated health data into United Kingdom electronic health records

open access: yesJournal of Innovation in Health Informatics, 2019
The integration of patient/person generated health data into clinical applications is a key strategic priority internationally. However, despite agreement on the overall direction of travel, there are still a range of challenges that inhibit progress in ...
Kathrin Cresswell   +4 more
doaj   +1 more source

Thomas S. Schelling: game theory and indirect communication [PDF]

open access: yes
In their recent work Thomas S. Schelling (2007, 2010), reiterating original arguments about game theory and its applications to social sciences. In particular, game theory helps to explore situations in which agents make decisions interdependent ...
Estrada, Fernando
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

L’incertitude dans l’utilisation des médias géolocalisés : étude de deux applications reliées à la mobilité urbaine

open access: yesNetcom, 2015
Drawing from the differentiation between strategic and tactical practices, developed by Michel de Certeau (1990), and the concept of hybrid space (De Souza e Silva, 2006; Nova, 2009), this paper aims to distinguish the various relationships to ...
Julia Salles
doaj   +1 more source

Some Notes on Learning in Games with Strategic Complementarities [PDF]

open access: yes
Fictitious play is the classical myopic learning process, and games with strategic complementarities are an important class of games including many economic applications. Knowledge about convergence properties of fictitious play in this class of games is
Ulrich Berger
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

IT-Business Alignment Challenge: Enterprise Architecture as an Enabler for Strategic Alignment

open access: yesمدیریت تولید و عملیات, 2011
One of the most important organizational challenges is the strategic alignment between information technology (IT) and business objectives. Organizations have deployed different approaches to achieve strategic alignment and competitive advantage ...
Hanieh Sadat Beiryaei, Mona Jamporazmey
doaj  

The activity-based costing method developments: state-of-the art and case study [PDF]

open access: yes
This paper analyses the management accounting applications which try to improve the Activity-based Costing method. In the first part, we describe them using the Strategic Management Accounting stream.
Grégory Wegmann, Nozile Stephen
core  

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