Results 141 to 150 of about 29,308,301 (338)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Harnessing emerging technologies in defence: strategic approach for ASEAN unity

open access: yes
At a retreat in February 2025, ASEAN’s defence ministers adopted a joint statement on cooperation in artificial intelligence in the defence sector. Muhammad Faizal notes that the joint statement implies the need for a strategic approach to harnessing ...
Muhammad Faizal Bin Abdul Rahman
core  

The Systems Thinking Approach to Strategic Management [PDF]

open access: yesSystems
This paper presents a review of the field of systems thinking and strategic management The evolution of the areas of interest between systems thinking and strategic management follows similar patterns with more prescriptive developments occurring within the 1960s until 1980s; then, an increasing focus on emergence and transformation emerged in later ...
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Strategic Value-Driven Approach toward Brand in Iranian Agile Companies [PDF]

open access: yes, 2016
The objective of the research is to design and explain a strategic model based on customer value proposition and employee value proposition in Iranian agile companies. Based on a qualititaive metheod i.e.
Babak Moradi   +3 more
core  

Psychotherapy of feeling of guilt in terms of different approaches: strategic and narrative approaches, internal family systems, psychodrama and schema therapy

open access: yesПсихология и Психотерапия Семьи, 2017
The article considers the possibilities of applying different approaches to the psychotherapy of feelings of guilt. Strategic and incremental approaches, systemic family therapy of subpersonalities, psychodrama and scheme-therapy are presented ...
Tatiana Rytsareva   +4 more
doaj  

Problem of systematization of strategic management methods

open access: yesВекторы благополучия: экономика и социум
Relevance. Describing the system of strategic management, it is necessary to refer to the fundamental scientific principles that are universal and find their application in various fields of knowledge.
O.V. Simagina, Yu.V. Vershinina
doaj   +1 more source

Gender mainstreaming: a strategic approach

open access: yes, 2018
As a starting point, this paper recognizes the importance of gender equity for economic growth, societal well-being, and sustainable development. Moreover, the paper acknowledges that while women make up half of the world's population, most policy, program and government initiatives affect women and men differently.
Thomas, Margo   +5 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Strategic Entrepreneurship and Value Creation: A Comparative Case Study

open access: yes, 2011
[[abstract]]This paper examines the relationship between strategic management and entrepreneurship and develops insights that advance the boundaries of the two fields and addresses an alternative strategic entrepreneurship framework.
Yee-Yeen Chu; Shih-Chang Hung 
core  

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