Results 21 to 30 of about 1,874 (165)

Linguistic and Sociolinguistic Competence of Senior High School Students

open access: yesRecoletos Multidisciplinary Research Journal, 2018
This study aims to identify whether the Senior High School students are Linguistic, Discourse, Sociolinguistic or Strategic Competent in English. Quantitative and qualitative research methods were used to collate a survey that would sure mend the study ...
Ionell Jay R. Terogo   +4 more
doaj   +1 more source

Strategic Competence Model for Understanding Smart Territorial Development

open access: yesSocieties, 2023
In this paper, the authors propose a multi-level model for the strategic competence of territorial units, which can help explain why some territorial units manage to respond appropriately to global challenges and thrive while others fail.
Urška Fric   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Smart Learning Models of Certified Legal Translators and Interpreters in China

open access: yesComparative Legilinguistics, 2018
Legal translation has played an important part in the contact between different people and countries in the history, and it is playing an even more significant role in the increasingly globalized world nowadays.
Ming XU
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Profile of Strategic Competence Education for Sustainable Development Based on Gender in Nature Schools

open access: yesQuagga
To advance sustainable development, competencies cannot be taught, but students must develop through experience and reflection to acquire action. One of the important competencies to be applied in education is strategic competence.
Dina Mardiana   +3 more
doaj   +1 more source

Strategic Competence and L2 Speaking Assessment

open access: yesWorking Papers in Applied Linguistics and TESOL, 2015
Assessing second language speaking has long been an important part of language testing in both large-scale assessment settings and in smaller scale classroom-based assessments.
Yuna Seong
doaj   +1 more source

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