Results 41 to 50 of about 1,221,883 (313)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Strategic cost management of baking companies [PDF]
Досліджено особливості стратегічного управління витратами хлібопекарських підприємств в сучасних ринкових умовах господарювання. Зазначено, що концепція стратегічного управління витратами виникла в результаті поєднання таких трьох напрямків стратегічного
Kostetska, Natalia
core
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
An integrated model for cash transfer system design problem [PDF]
This paper presents an integrated model that incorporates strategic, tactical, and operational decisions for a cash transfer management system of a bank.
Dasci, Abdullah +4 more
core
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Time planning and Cost Management in Strategic Alliances
The paper highlights a mutual support example out of ten simulations regarding strategic alliances based on the hypothesis that every partner allocates its resources and budget in an equitable manner according to total expected time (PERT).
Ana-Maria Giurea
doaj
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Strategic cost management as the main component of strategic management accounting
Представлен анализ влияния управления затратами на принятие стратегических управленческих решений и функционирование системы стратегического управленческого учета. В статье отражены преимущества стратегического управленческого учета, направленные на формирование системы современных знаний, которая объединяет учетные концепции по принятию эффективных
openaire +4 more sources

