Results 161 to 170 of about 6,666,805 (268)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Effects of Pre-Response Before COVID-19 Outbreak on Strategic Decision Making

, 2020
Jung JH, Kim D, Jung IH.
europepmc   +2 more sources

Strategic decision making in live streaming e-commerce through tripartite evolutionary game analysis. [PDF]

PLoS One
Xu Y, Qi J, Kong J, Zhang W.
europepmc   +1 more source

Neural Basis of Strategic Decision Making. [PDF]

Trends Neurosci, 2016
Lee D, Seo H.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Enhancing strategic decision-making in built asset management through BIM-Enabled asset information modelling (AIM) for public buildings in Ethiopia: A fuzzy-AHP analysis. [PDF]

Heliyon
Desbalo MT, Woldesenbet AK.
europepmc   +1 more source

QuantumIS: A Qualia Consciousness Awareness and Information Theory Quale Approach to Reducing Strategic Decision-Making Entropy. [PDF]

Entropy (Basel), 2019
Rodger JA.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Effective waste management in service industry: Fuzzy-based modelling approach for strategic decision-making. [PDF]

Waste Manag Res
Dinçer H, Yüksel S, Eti S, Gökalp Y, Mikhaylov A, Karpyn Z.   +5 more
europepmc   +1 more source

A resource of potential drug targets and strategic decision-making for obstructive sleep apnoea pharmacotherapy. [PDF]

Respirology, 2017
Horner RL, Grace KP, Wellman A.
europepmc   +1 more source