Results 131 to 140 of about 1,832,046 (296)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Knowledge and Technology – Implications for a strategic Design – Croatian Case [PDF]

open access: yes
Globalization and internationalization processes continuously increase the quantity of information. All the information is quickly and easily accessible, and the problem is no longer scarcity of information, but its surplus.
Glavaš, Jerko, Lamza - Maronić, Maja
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The protective benefits of tsunami mitigation parks and ramifications for their strategic design. [PDF]

open access: yesProc Natl Acad Sci U S A, 2020
Lunghino B   +6 more
europepmc   +1 more source

EVALUATING STRATEGICAL SPATIAL PLANNING APPROACH IN CASE OF ISTANBUL [PDF]

open access: yes
In Turkey, The law of Institutional Strategic Planning (ISP) issued in order to compliance with European Union is unfortunately insufficient recovering spatial-oriented strategic planning (SSP) decisions.
Rahmi ERDEM, Sinan LEVEND
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Using SimVenture in Fashion and Textiles [PDF]

open access: yes
A case study from the Developing Enterprising Students project, a strategic teaching and learning project at the University of Huddersfield. The case study is based on an interview with Jo Conlon, Senior Lecturer in the Department of Design, School of ...
Jensen, Kathrine, Yip, Daniel
core  

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